Protein Alignment Sema1b and sema4b

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_031755080.1
• Gene: sema4b / 100489037
• XenbaseID: XB-GENE-922109
• Length: 850
• Species: Xenopus tropicalis
• Alignment Length: 584
• Identity: 170/584 - (29%)
• Similarity: 284/584 - (48%)
• Gaps: 88/584 - (15%)

  Fly    53 FIGNSTDYFK--ILDHNDEFVLVGAKDVIYNVSLNGLKEI---ARLEWHSTDADRELCALKGKH- 111
            |..:...||.  :|..:...:.|||::.:::::.......   :::.|.:.:..::.||.|||.
 Frog    56 FEADGVTYFTTLLLGKDGSALYVGAQEALFSLNSTDFTSADYHSKIAWQADEEKKKECAFKGKDP 120

  Fly   112 EWDCHNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQG 176
            :.||.||:::.....:..:..|||.::.|.|. |..:...|.|..:.||      .:..|.:.:
 Frog   121 QRDCQNYIKILLQLNSTHLYTCGTFAFSPTCT-YIKISDFSLEKNALGH------PILEDGKVR- 177

  Fly   177 LCPYSPAHNSTYAFADGHLYSATVADFSGGDPLIYREN-----LRTEQYDLKQLNQPDFVGA--- 233
             ||:.|.:|||....||.:|:.||::|.|.:|:||:.:     |:||. .|..|..|.|||:
 Frog   178 -CPFDPEYNSTAIMVDGEMYAGTVSNFQGNEPIIYKSHDSRITLKTEN-SLYWLQDPAFVGSAYI 240

  Fly   234 ---------IERNGYVLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLN 289
                     :..:..:.:||.|...|...|...:.||:|||||.|.||.....:.|||||||:|.
 Frog   241 QESLPKGNPVGDDDKIYYFFSETGKEFDFFENTIVSRIARVCKGDLGGERVLQRRWTSFLKAQLI 305

  Fly   290 CSVPGE-FPF-YFDEIQAISPIVESGSKSLIYAVFTTSVN--AIPGSAVCAFNVDDILAAFDGEF 350
            ||.||: ||| ...::..::|..|....::.|.|||:..|  ....||||||::|::..||:|.|
 Frog   306 CSCPGDGFPFNVLKDMFVLTPGEEHWKSTIFYGVFTSQWNKGGAGSSAVCAFSMDEVQNAFNGLF 370

  Fly   351 KSQKDSQSHWLPVEREQVPKPRPGQCV----EDSRTLTSI-----AVNFIKNHPLMEEAVPAVHG 406
            |........|. .....||:||||.|:    .|.:..:|:     .:||:|:|.||:.   |:..
 Frog   371 KEVNRETQQWY-TYTNSVPEPRPGACITNSARDKKINSSLQMPDRVLNFVKDHFLMDS---AIRS 431

  Fly   407 RPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVI 471
            :|||.:..:.::..::   .:|:.|... |||::.|||||::.|.:::     |..|.     :|
 Frog   432 QPLLLQSQIRYQQISV---QRVRGLKKT-YDVLFLGTDDGRLHKAVSV-----NKMVH-----II 482

  Fly   472 SEMQVLPLGTPIRELVISTSKNSLVVVSDGSLVSVPLHHCSHIVDCLGCLSLQDPICAWDLQ--- 533
            .|:::.....|::||::..||..:...|..::|.||:.:||....|..|:..:||.|||:.:
 Frog   483 EEIKLFQDMQPVQELLLDPSKGLIYASSRSAVVQVPVSNCSMYRSCGECILSRDPYCAWNKKGCH 547

  Fly   534 -----THECKNLATSQH------KFGTKTYLQSLNSTK------KAAALLCPHIPRDAPGAETV 580
                 ||:.||    ||      ...|..:.:..|||:      |.....|..|..::..|.|:
 Frog   548 SVPHHTHDTKN----QHWVQDIEDANTDAHCKPSNSTEAIGRAGKPDESECQEISMESNPANTL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	145/491 (30%)
		PSI	510..>537	CDD:214655	11/34 (32%)
sema4b	XP_031755080.1	Sema	55..520	CDD:472829	146/491 (30%)
		PSI	521..564	CDD:214655	15/46 (33%)
		Ig	594..669	CDD:472250	4/14 (29%)
		Ig strand B	605..609	CDD:409456	1/3 (33%)
		Ig strand C	617..621	CDD:409456
		Ig strand E	637..640	CDD:409456
		Ig strand F	650..655	CDD:409456