DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sema1b and dok2

DIOPT Version :9

Sequence 1:	NP_001163178.1	Gene:	Sema1b / 37007	FlyBaseID:	FBgn0016059	Length:	770	Species:	Drosophila melanogaster
Sequence 2:	XP_002932742.2	Gene:	dok2 / 100487659	XenbaseID:	XB-GENE-982227	Length:	416	Species:	Xenopus tropicalis

Alignment Length:	162	Identity:	36/162 - (22%)
Similarity:	50/162 - (30%)	Gaps:	39/162 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 GHLYSATVAD------FSGGDPLIYRENLRTEQYDLKQLNQPDFVGAIERNGYVLFFFRELSMEV 251
            |.||.||.:.      |.|..|  .....:.|.:.|.||:  :.|...||||      .....:.
Frog    28 GVLYEATCSGLARLEMFEGSQP--PDSGRKPECWKLLQLS--ECVSVSERNG------EGSPKDT 82

  Fly   252 MNFGKAVYSRVARVCKNDRGGPYSHGKSWT------SFLKARL----NCSVPGEFPFYFDEIQAI 306
            .:|......||..:.......|     .|.      :|.:.||    ..|.|.|...:..|.:..
Frog    83 RSFCIETAQRVYLLASETSEQP-----GWVKALCSLAFPQERLPLERKTSQPPESGLHLQENELY 142

  Fly   307 SPIVESGSKSLIYAVFTTSVNAIPGSAVCAFN 338
            |...|:|        |...:.....|..|..|
Frog   143 STTRETG--------FVVRIRPTEASVRCGLN 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	36/162 (22%)
Sema1b	NP_001163178.1	PSI	510..>537	CDD:214655
dok2	XP_002932742.2	PH-like	7..115	CDD:388408	22/101 (22%)
dok2	XP_002932742.2	PH-like	150..244	CDD:388408	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010