Protein Alignment Sema1b and sema6d

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001120152.1
• Gene: sema6d / 100145190
• XenbaseID: XB-GENE-967070
• Length: 1084
• Species: Xenopus tropicalis
• Alignment Length: 831
• Identity: 252/831 - (30%)
• Similarity: 373/831 - (44%)
• Gaps: 204/831 - (24%)

  Fly    56 NSTDYFKILDHNDEFVLVGAKDVIYNVSLNGLKEI-----ARLEWHSTDADRELCALKGKHEWDC 115
            :|.|:..:|...|...:.| :|.:|.::||.:.:.     .||.|.|..|||:.||:||||:.:|
 Frog    55 HSLDFQLMLKIRDTLYVAG-RDQVYAINLNEVPKTEVTPSRRLTWRSGQADRKNCAMKGKHKDEC 118

  Fly   116 HNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPY 180
            |||::|:..|.:..|.:||||::.|.||:|              ..:...|: ..::.....||:
 Frog   119 HNYIKVFVPRNDEMVFVCGTNAFNPMCRYY--------------RLNTFDYD-GEEISGLARCPF 168

  Fly   181 SPAHNSTYAFADGHLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAIERNGYV 240
            .....:...||||.|||||:|||...|.:|||.     .|||.:||.|.|.:|.|:.|||...|:
 Frog   169 DARQTNVALFADGKLYSATMADFQASDAVIYRSMGDGFALRTIKYDSKWLKEPHFLHAIEYGNYI 233

  Fly   241 LFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYS-HGKSWTSFLKARLNCSVPGEFPFYFDEIQ 304
            .|||||:::|..|.||||:|||||:||||.||... ..|.||||:||||||||||:..||||.:|
 Frog   234 YFFFREIAVEHNNLGKAVHSRVARICKNDLGGSQRVLEKHWTSFVKARLNCSVPGDSFFYFDVLQ 298

  Fly   305 AISPIVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVP 369
            :|:.|:|......:..||||.:|:|||||||||.:|||...|.|.||.||...|.|..|..::||
 Frog   299 SITDIIEINGIPTVVGVFTTQLNSIPGSAVCAFTMDDIEKVFRGRFKEQKTPDSVWTAVPEDRVP 363

  Fly   370 KPRPGQCV-----EDSRTLTSI---AVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHP 426
            |||||.|.     |..|:.|..   .::|||:||||:.|:|::...|..||..:.:||||:|
 Frog   364 KPRPGCCARHGYGEGYRSSTEFPDETLSFIKSHPLMDSAIPSIIEEPWFTKTRVRYRLTAVA--- 425

  Fly   427 QVKSLSGAY--YDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLG--------- 480
             |..|:|.|  |.|::.|::.|.|.|.  :..|:|.|..|   :|::.|:......
 Frog   426 -VDHLAGPYLNYTVMFVGSEAGVVLKI--LAKTNPFSLND---SVLLEEIDAYNRAKCSGNSEED 484

  Fly   481 TPIRELVISTSKNSLVVVSDGSLVSVPLHHCSHIVDC-LGCLSLQDPICAW-------------- 530
            ..:..|.:....::|.|...|.:|.:||..|.....| ..|:..:||.|.|
 Frog   485 RKVISLQMDRDHHALFVAFSGCIVRLPLSRCERYGSCKKSCIGARDPYCGWLNHESCGRVKPGMF 549

  Fly   531 -----------DLQTHECKNL----ATSQHK-FGTKT---YLQSLNSTKKAAALLCPHI-----P 571
                       .:|..:|.::    .|..:| ||..|   .:.|.:.|..::.::.|.:     |
 Frog   550 FGYEQDVEYGNTVQLGDCHDILPTATTPDYKIFGDPTSDIEVPSTSVTTTSSPVILPKVIGSWKP 614

  Fly   572 RDAPGAETVSFVTMAPPPTEE--------QKLLYSNVGSSQGNQPSLEQQPTGGDDFGLNKITLT 628
            | ..|:.  .|:....|.|.|        ||.:...|.|...||
 Frog   615 R-MTGSR--KFIYQDDPNTSEYIDPLTGVQKGVRWEVQSGDANQ--------------------- 655

  Fly   629 SMDPDDIMPNLNDPQKSTASVDEIKYASTPSFMLLTTIVFFTFLVGG-IAGIC--CVK----AKS 686
                   |.::|                     :|.|.|...|::|. |||:.  |.:    .|:
 Frog   656 -------MVHMN---------------------VLITCVLAAFVLGAFIAGVIVYCYREMFVRKT 692

  Fly   687 RLMEAQMDESH------------RNHFGKPMQFKHQN-------------------TGKDINLLM 720
            |.:....:.:.            ...|..|::..||:                   .|:..:::|
 Frog   693 RKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYHQSIDSPKHYTNILTSRKELPPNGETKSMMM 757

  Fly   721 GSN-------AYTTTQKTP-----NLDLEKDRSHECKNSTEHLEKELPCKT 759
            .|.       |..|.:.||     :|...|::..:..|:.....||.|.|:
 Frog   758 DSQGQPPELAALPTPESTPVLHQKSLQPIKNQWEKTHNNLNISRKETPLKS 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	191/484 (39%)
		PSI	510..>537	CDD:214655	8/52 (15%)
sema6d	NP_001120152.1	Sema_6D	49..513	CDD:200530	190/482 (39%)
		PSI	514..>543	CDD:396154	7/28 (25%)
		ARG80	<829..1080	CDD:227400