Protein Alignment Sema1b and sema4g

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_002938767.1
• Gene: sema4g / 100038182
• XenbaseID: XB-GENE-856594
• Length: 830
• Species: Xenopus tropicalis
• Alignment Length: 818
• Identity: 211/818 - (25%)
• Similarity: 349/818 - (42%)
• Gaps: 169/818 - (20%)

  Fly    19 MILLITLSGLTIVAGWMP--------DVKPDLQTKQDKV--LAHFIGNSTDYFKILDHNDEFVL- 72
            :::|.|:|    |.|:..        |..|.:....:::  |..|....::|..:|..::..:|
 Frog     9 LVVLCTVS----VIGYYSTDGSPMGLDATPRITVTYNEILDLRRFSSRVSNYSTLLLEDERGILY 69

  Fly    73 VGAKDVIYNVSLNGLKEIAR--LEWHSTDADRELCALKGK-HEWDCHNYLRVYALRPNGEVLLCG 134
            |||:..|::::...:.:..:  :.|..|....:.|..||| ::.:|.|::|:........:.:||
 Frog    70 VGARGAIFSLNSTNISQRYQKAIPWEVTAQKHDECIKKGKNNQTECFNHIRLLLRFNETHLYVCG 134

  Fly   135 TNSYKPRC-----RHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFADGH 194
            |.::.|.|     |.:.   :|||..                 |.:..|||.||........||.
 Frog   135 TYAFSPLCSFIDSRTFV---LSSETE-----------------EGKEKCPYDPAKGYVGLLVDGG 179

  Fly   195 LYSATVADFSGGDPL---IYRENLRTEQYDLKQLNQPDFVGA----------IERNGYVLFFFRE 246
            ||:|::.:|.....:   :.:.:|:||:.:|..||.|:||.|          :..:..:.:||.|
 Frog   180 LYTASLYEFRNLPDIRRNLLQRSLKTEESNLHWLNDPEFVSAALVQESMNVEVGDDDKIYYFFNE 244

  Fly   247 LSMEVMN-FGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGEFPFYFDEIQAISPIV 310
            ..:|..: |..:..:.||||||:|.||.....|.|||||||||.|.:    |||  |:...:..:
 Frog   245 KVVEENSAFLGSKTASVARVCKDDMGGKKILQKKWTSFLKARLVCYM----PFY--EVLKSAYTL 303

  Fly   311 ESGS--KSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRP 373
            |.||  .::.|..|......:..||:|.:::.||...|:|.:...:.|...|...|.| ||.|||
 Frog   304 ELGSWDTTIFYGAFILQWKNMEESAICRYSISDIQKVFEGPYMEYQYSSRKWSRYEGE-VPSPRP 367

  Fly   374 GQCVED---------SRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVK 429
            |.|:.:         |:.|.:..::|:|.||||.|.|..|..:|||.|.|:.:  |.||| .:||
 Frog   368 GSCITNEFRMNGFNTSQDLPNNVLDFVKLHPLMYEKVRPVGEQPLLVKKNIIY--TRIAV-DRVK 429

  Fly   430 SLSGAYYDVIYSGTDDGKVTKFINILS-THPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKN 493
            :|:..||||::.|||||.:.|.:.|.| .|           :|.|:||.....|:..||||..:|
 Frog   430 ALNDEYYDVLFLGTDDGWIHKAVVIGSMVH-----------IIEEIQVYKFPQPVENLVISKKQN 483

  Fly   494 SLVVVSDGSLVSVPLHHCSHIVDCLGCLSLQDPICAWDLQTHECKNLATSQHKFGTKTYLQS--- 555
            :|.:.:...::.:||..||....|..|:..::|.||||  .|.|:::..::::......:|:
 Frog   484 ALYIGAQSGVLQIPLFGCSQYTSCYDCILARNPYCAWD--GHACRDIIGAKNRTQMTQDMQNGNG 546

  Fly   556 --LNSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTEEQKLLYSNVGSSQ----GNQPSLEQQP 614
              ||||...|  |...:.|...|.:.:.           |..|.||:...|    |.....:.:
 Frog   547 GCLNSTDDGA--LKKRVRRVLKGNDVLL-----------QCELRSNLARPQWYVNGTDKLYDSE- 597

  Fly   615 TGGDDFGLNKITLTSMDPD-----DIMPNLNDPQKSTA--------SVDEIKYASTPS------- 659
             |....|::.:.:|...|:     ......|..|...|        .:.:.|..|||:
 Frog   598 -GHTRLGVDGLLITDTLPEHSGEYSCYSEENGLQSLVAVYSLNVLLELPKEKNYSTPTPIIQLPT 661

  Fly   660 ----------FMLLTTIVFFTFLVGGIAGICCVKAKSRLMEAQMDESHRNHFG------------ 702
                      |:.::||.        |.|:.||.....|:.....:..:..:.
 Frog   662 AAPQSTGNIQFIYISTIT--------ILGVLCVVLSIVLLYVSCQQKKKGKYAVRNSRSTNVELQ 718

  Fly   703 -KPMQFKHQNTGKDINLLMGSNAYTTTQKTPNLDLEKD 739
             ...|||.:  .:|:|............:.|.|...||
 Frog   719 TVSSQFKEK--AEDLNSYSDGCLQIIPGEAPTLSPHKD 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	148/490 (30%)
		PSI	510..>537	CDD:214655	10/26 (38%)
sema4g	XP_002938767.1	Sema	47..499	CDD:472829	148/492 (30%)
		PSI	500..>527	CDD:214655	11/28 (39%)
		Ig_Sema4B_like	557..643	CDD:409456	16/98 (16%)
		Ig strand A	557..563	CDD:409456	1/5 (20%)
		Ig strand B	567..575	CDD:409456	2/18 (11%)
		Ig strand C	581..587	CDD:409456	1/5 (20%)
		Ig strand C'	589..592	CDD:409456	1/2 (50%)
		Ig strand D	599..603	CDD:409456	0/3 (0%)
		Ig strand E	605..612	CDD:409456	1/6 (17%)
		Ig strand F	618..627	CDD:409456	0/8 (0%)
		Ig strand G	630..643	CDD:409456	2/12 (17%)