Protein Alignment Sema1b and sema5bb

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_001340298.5
• Gene: sema5bb / 100000009
• ZFINID: ZDB-GENE-130530-778
• Length: 1098
• Species: Danio rerio
• Alignment Length: 561
• Identity: 192/561 - (34%)
• Similarity: 279/561 - (49%)
• Gaps: 73/561 - (13%)

  Fly    20 ILLITLSGLTIVAGWMPDVKPDLQTKQDK------------------VLAHFIGNSTDYFKI-LD 65
            :::..|..|.:|....|...||....|.:                  :.:..:....||..: ||
Zfish    16 LVIFHLLFLPVVTSQTPSSPPDTPDPQPEECRRKMHPVTSYTALSPWLFSFSVPGVNDYSPLTLD 80

  Fly    66 HNDEFVLVGAKDVIYNVSLNGLKEIARLEWHSTDADRELCALKGKHEWDCHNYLRVYALRPNGEV 130
            .:...::|||::.::.:||:.:..:...||...:..|..|..|||.|.:|.||:||..|  ||..
Zfish    81 LSRSQLIVGARNHLFRLSLSNISLLQATEWGVDETTRRSCQSKGKTEDECQNYVRVLLL--NGSR 143

  Fly   131 LL-CGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFAD-G 193
            |. ||||::.|.|......::||               |...:.....|||.|.||||....: |
Zfish   144 LFTCGTNAFMPVCVTRPVTDISS---------------VLDSISGVARCPYDPRHNSTAMITESG 193

  Fly   194 HLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAIERNGYVLFFFRELSMEVMN 253
            .:|:|||.|||..||:|||.     .|||.||:.|.||.|.|:.|.|.:.:...|.||.::| .:
Zfish   194 EVYAATVTDFSSRDPIIYRSLGNMPPLRTAQYNSKWLNDPHFISAYEVSRFTYVFLRENAVE-QD 257

  Fly   254 FGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGEFPFYFDEIQAISPIVESGSKSLI 318
            .||.|:|||||||:||.||.:....:||:|:|||||||..|:.|||:.|:|:...:.|   :.||
Zfish   258 CGKTVFSRVARVCQNDIGGRFLLEDTWTTFMKARLNCSRSGDVPFYYHELQSTFYLPE---QDLI 319

  Fly   319 YAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPG-QC--VEDS 380
            |.||||:||:|..|||||||:..|..||:|.|:.|::.::.||     ..|.|.|. ||  |.||
Zfish   320 YGVFTTNVNSIAASAVCAFNLSAITQAFNGPFRYQENPRTSWL-----STPNPVPNFQCGTVNDS 379

  Fly   381 ---RTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDVIYSG 442
               ..||..::...:...||.:.|..:...||:.:.|:  |.:.:||  .:.......|.|:|.|
Zfish   380 GPGANLTERSLQDAQRLFLMSDVVQPISTDPLVMQDNI--RFSKLAV--DIVQGRDTLYHVMYIG 440

  Fly   443 TDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGT---PIRELVISTSKNSLVVVSDGSLV 504
            |:.|.:   |..|||:..|    |:...:.||.:|| |.   ||..|.|..|..||.|.....::
Zfish   441 TEYGTI---IKALSTNNKS----LRGCYLEEMNILP-GNKQEPILNLQILHSDRSLFVGLPSRVL 497

  Fly   505 SVPLHHCSHIVDCLGCLSLQDPICAWDLQTHECKNLATSQH 545
            .:||..||:.:....||..:||.|.||.:...|..:..|.:
Zfish   498 KIPLERCSNYITEQDCLGARDPYCGWDRKEKRCTTIEDSSN 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	174/472 (37%)
		PSI	510..>537	CDD:214655	9/26 (35%)
sema5bb	XP_001340298.5	Sema	66..502	CDD:301699	173/473 (37%)
		PSI	503..550	CDD:279745	11/36 (31%)
		TSP1	561..613	CDD:214559
		TSP1	616..669	CDD:214559
		TSP1	674..719	CDD:214559
		TSP1	806..858	CDD:214559
		TSP1	869..915	CDD:214559
		TSP1	918..960	CDD:214559

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810