DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment P32 and cri-3

DIOPT Version :9

Sequence 1:	NP_611243.1	Gene:	P32 / 37006	FlyBaseID:	FBgn0034259	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001379055.1	Gene:	cri-3 / 175441	WormBaseID:	WBGene00010303	Length:	236	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	71/201 - (35%)
Similarity:	106/201 - (52%)	Gaps:	22/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ELVEFLTEEIVAERKVQ----KGKTVPSTLDGFAVKLTGADVELTKQTDKEKVVVSFNVNHTVDS 132
            ||.:.|..||.||:::.    :|...| |..||.|....|:|.|||:...|.::|.|||||:||.
Worm    41 ELQQALNREIEAEQQLSSDNLQGAVAP-TFAGFQVTNKDAEVRLTKKNGSEDILVVFNVNHSVDM 104

  Fly   133 EEEPEINPN---ADKPDLGEMRSKPQFEVDIIKGNSTLSFTCSFLQGEAQEGEYNDVFSIDEMAI 194
            :|..:..|:   |..|     .:.|.|.|:|.||:..|.|....:..:.|..||:  |.::|..:
Worm   105 DEGFDDEPSQAVAPVP-----VAMPPFTVEITKGDQRLCFHLELVPVDDQPDEYD--FRVEEFYV 162

  Fly   195 FEGEWN------DKVYAVAGDVLDGYLYDLL-INLLEEKGISQEFAEKLSDLATAHEHTSYIGLL 252
            .....|      .:|||.:|..:|..|:||| :..|||:|:...|.:.|...||.:||:.|:|||
Worm   163 APSAKNGNEDVPSEVYASSGKYIDPDLHDLLFVRYLEERGLDARFCKTLVAYATHYEHSQYVGLL 227

  Fly   253 EKLSKF 258
            :|:.||
Worm   228 DKIKKF 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
P32	NP_611243.1	MAM33	68..253	CDD:280488	67/194 (35%)
cri-3	NP_001379055.1	MAM33	46..228	CDD:396762	65/189 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157444
Domainoid	1	1.000	98	1.000	Domainoid score	I4512
eggNOG	1	0.900	-	-		E1_KOG4024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31023
Inparanoid	1	1.050	101	1.000	Inparanoid score	I3568
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48658
OrthoDB	1	1.010	-	-		D504912at33208
OrthoFinder	1	1.000	-	-		FOG0006976
OrthoInspector	1	1.000	-	-		oto17583
orthoMCL	1	0.900	-	-		OOG6_107765
Panther	1	1.100	-	-	LDO	PTHR10826
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R681
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840