Protein Alignment eIF3c and TIF3C2

DIOPT Version :9

• Sequence 1: NP_001286545.1
• Gene: eIF3c / 37005
• FlyBaseID: FBgn0034258
• Length: 910
• Species: Drosophila melanogaster
• Sequence 2: NP_188926.4
• Gene: TIF3C2 / 821858
• AraportID: AT3G22860
• Length: 805
• Species: Arabidopsis thaliana
• Alignment Length: 919
• Identity: 288/919 - (31%)
• Similarity: 453/919 - (49%)
• Gaps: 195/919 - (21%)

  Fly     2 SRFFA-NGSESESESSEEEIQATNFNKASAFQFSDDE----EEVKRVVRSTKEKRYENLTSIIKT 61
            ||||| :|||||.||..|:.:....|........|.|    .:.||||:..|:||:|.:.:.|:.
plant     5 SRFFAQSGSESEDESDFEKEEVEGNNTRYLADLPDGEICCGMDTKRVVKPKKDKRFEEMANTIEN 69

  Fly    62 IRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRK 126
            :::...|.|......:||.|.:...|::.         ||..||:.|..||||:||  ::.:.::
plant    70 MKHAMNINDCVYLQETFEKLNKQISKSVK---------TPTLYIKTLVMLEDFLNE--DNMKTKE 123

  Fly   127 NLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAP--DQESEAEDEVVALESDGGDAGDDSDAGV 189
            .:|.:|||:|..:|||::|....:::|:.||||:|  :.:.|.|:|||
plant   124 KMSTSNSKALNAMRQKLKKNNLQYQEDIKRFRESPEIEDDDEYEEEVV----------------- 171

  Fly   190 KPTEAVPKAVKSAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKEEK 254
                                  :||.|::.|:
plant   172 ----------------------EDSADNVSWE--------------------------------- 181

  Fly   255 DDDKRKDKRKEQKTKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSAR 319
                            ...:.|.|:..|..|.|                       |..||.:||
plant   182 ----------------MLFSLDHEEITWNMVNK-----------------------KFKEIRAAR 207

  Fly   320 GKKRTDRRLQI-------DLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQ-KISEPMKLEH 376
            ..||....|::       ....:|..|:..    .|..|:|.|::|||.::.|. .:|..|.::.
plant   208 WSKRRSSSLKLKPGETHAQKHMDLTKIAKT----PAQKVEILFSVISAEFNVNSGGLSGYMPIDV 268

  Fly   377 WALLLEVMQSMMKLLLANADIIMSESVAEEHEEYATSPFY-----VRGCPLAAVERLDDEFVKLL 436
            |...:..|.:::.:|:...:|::.::|..:.:|.:....|     |.|..:|.:|:::.||.|.|
plant   269 WKKCVVNMLTILDILVKYYNIVVDDTVEPDEKETSKPAAYDGTIRVSGNLVAFLEKIETEFFKSL 333

  Fly   437 KECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYK----FD----- 492
            :..|||:||||.|||||...:...:.:..|.||:|.:....::....:|.:|||    ||
plant   334 QCIDPHTNDYVERLKDEPMFLALAQSIQDYLERTGDSKAASKVAFILVESIYYKPQEVFDAMSKL 398

  Fly   493 ----------------------PEVLKKKRGELPATTSTSVDVMDKLCKFIYAKDDTDRIRTRAI 535
                                  .|::.:|    |....:|..:||.|..||| |:..:|.:.||:
plant   399 ADEEIEEANEESGSSSSSFIVVAEIVPRK----PTFAKSSRAMMDTLVSFIY-KNGDERTKARAM 458

  Fly   536 LAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLV 600
            |..||.||:.||:..||||:||||||:||...|.:|:||:||.||.|||||||.|.:.::|.||.
plant   459 LCDIYQHALMDNFVTARDLLLMSHLQENIQHMDISTQILFNRTMAQLGLCAFRVGMITESHSCLS 523

  Fly   601 DLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIA 665
            :|....:.:|||.||:...|.||::.||..:|::.|:|:||:|||||||.|||..|||||:|.:|
plant   524 ELYSGNRVRELLGQGVSQSRDHEKTTEQMLMERRTQIPYHMNINLELLEAVYLTCAMLLEVPNMA 588

  Fly   666 AHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTK 730
            |:..|::.:.|||...:.|..||:|:...|||::|.||:||.:|:..||:|. |..::|   :..
plant   589 ANSHDSKHKPISKNIQRLLEKSEKQAFTAPPENVRVHVIAATRALIKGNFQE-AFSVLN---SLD 649

  Fly   731 VWDLFYESDRVREMLTKFIKEESLRTYLFTY-SNVYTSISIPSLAQMYELPVPKVHSIISKMIIN 794
            :|.||...|.:.:|:...|.|.:|||||||| |:.|.|:|:..||:|:::....|:||:|||:||
plant   650 IWRLFKNRDSILDMVKASISEVALRTYLFTYSSSCYKSLSLAELAKMFDISESHVYSIVSKMMIN 714

  Fly   795 EELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDR 859
            :||.|:.|.|::.:..|..:.:|.|:||.|..:|:..|.:.||...:.|.|        |...|.
plant   715 KELNATWDQPTQCIVFHEVQHNRAQSLAFQITEKLATLAESNESAMESKTG--------GVGLDM 771

  Fly   860 GYNRNQNNQ 868
            ...|.:|:|
plant   772 TSRRRENSQ 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3c	NP_001286545.1	eIF-3c_N	24..671	CDD:283193	201/696 (29%)
		PAM	744..823	CDD:214803	35/79 (44%)
TIF3C2	NP_188926.4	eIF-3c_N	32..593	CDD:283193	200/691 (29%)
		PINT	663..752	CDD:214509	38/88 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	344	1.000	Domainoid score	I236
eggNOG	1	0.900	-	-		E1_KOG1076
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2781
Inparanoid	1	1.050	506	1.000	Inparanoid score	I308
OMA	1	1.010	-	-		QHG54519
OrthoDB	1	1.010	-	-		D273138at2759
OrthoFinder	1	1.000	-	-		FOG0003671
OrthoInspector	1	1.000	-	-		otm2914
orthoMCL	1	0.900	-	-		OOG6_101999
Panther	1	1.100	-	-	O	PTHR13937
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2545
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840