Protein Alignment CCHa1-R and QRFPR

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_937822.2
• Gene: QRFPR / 84109
• HGNCID: 15565
• Length: 431
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 90/375 - (24%)
• Similarity: 162/375 - (43%)
• Gaps: 52/375 - (13%)

  Fly    60 ENFSEL-----VTTETPYVPYGRRPETY----------IVPILFALIFVVGVLGNGTLIVVFLSV 109
            |.||.|     :|.|.....|..||..|          .:.:...|||.:.:.||..:..|....
Human     9 EQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRS 73

  Fly   110 RQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTA 174
            :.||.|.|.:|.||||:|||:....:|:.......:.|..|:|:|.:..|::..::...:.|:|.
Human    74 KAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTC 138

  Fly   175 LSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPA--LIGSNLKHLGINEKSI 237
            ::.:|:..:|.|.:....:...|..|.:.:     :||:|::.|.|.  :....:|:..:.||..
Human   139 IAVERHQGLVHPFKMKWQYTNRRAFTMLGV-----VWLVAVIVGSPMWHVQQLEIKYDFLYEKEH 198

  Fly   238 VICYPYPEEW-GINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHL-----MYSASVPGEIQGAV 296
            :.|.   ||| ...:.|.......::.:.:||:|:.:.|..|...|     :...||...|.|..
Human   199 ICCL---EEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKE 260

  Fly   297 RQVRARRK--VAVTVLAFVVIFGICFLPYHVFFLWFYF--WPTAQDDYNAFWHVLRIVAYCMSFA 357
            ....||:|  ..:.::..|.:|.:|:.|:||..:...:  :....||...  .::..:...:.|:
Human   261 MSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTI--KMIFAIVQIIGFS 323

  Fly   358 NSCANPVALYFVSGAFRKH-FNRYLFC-----------RGASG---RRKK 392
            ||..||:...|::..|:|: .:...:|           .|.||   .|||
Human   324 NSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKK 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	74/317 (23%)
		TM helix 1	83..109	CDD:320593	6/25 (24%)
		TM helix 2	116..142	CDD:320593	10/25 (40%)
		TM helix 3	154..184	CDD:320593	5/29 (17%)
		TM helix 4	201..221	CDD:320593	4/19 (21%)
		TM helix 5	252..277	CDD:320593	5/24 (21%)
		TM helix 6	300..330	CDD:320593	9/31 (29%)
		TM helix 7	345..370	CDD:320593	6/24 (25%)
QRFPR	NP_937822.2	7tmA_QRFPR	46..343	CDD:320333	73/306 (24%)
		TM helix 1	47..73	CDD:320333	6/25 (24%)
		TM helix 2	80..106	CDD:320333	10/25 (40%)
		TM helix 3	118..148	CDD:320333	5/29 (17%)
		TM helix 4	161..182	CDD:320333	7/25 (28%)
		TM helix 5	211..236	CDD:320333	5/24 (21%)
		TM helix 6	266..296	CDD:320333	8/29 (28%)
		TM helix 7	311..336	CDD:320333	6/24 (25%)