Protein Alignment CCHa1-R and npy2rl

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001314731.1
• Gene: npy2rl / 795311
• ZFINID: ZDB-GENE-111115-4
• Length: 373
• Species: Danio rerio
• Alignment Length: 349
• Identity: 91/349 - (26%)
• Similarity: 154/349 - (44%)
• Gaps: 60/349 - (17%)

  Fly    52 PLLDTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVP 116
            |||:.|.|   ::|:..:.            ::.:.::.|.::||:||..:|.|....:.:|.|.
Zfish    30 PLLELGDS---TKLLGVQV------------VLILAYSTIILLGVVGNSLVIYVVYKFKTLRTVT 79

  Fly   117 NTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYF 181
            |.:|.:||:|||||....:|.......:..|.:|..||....:.:.:::.||..||..::.||:.
Zfish    80 NFFIANLAVADLLVNTLCLPFTLAYTLLREWKFGQVLCFTLPYAQGLAVHVSTITLNVIALDRHR 144

  Fly   182 AIVDPLRKFHAHGGGRRATRMTLATAVSI----WLLAILCGLPALIGSNLKHLGI----NEKSIV 238
            .||     :|..      |||:..|...:    |:::.:...|..|   .:..||    .:.||.
Zfish   145 CIV-----YHLD------TRMSKDTCFLVIAITWVVSAVLASPLAI---FREYGIVDLSPDNSIE 195

  Fly   239 ICYPYPEEW------GINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVR 297
            :|   .|:|      ...|:.|.:||.    |.:||.:|:..|:.|...|....|..|......|
Zfish   196 VC---GEKWPDSSTDSTLYSISTLLLQ----YVLPLAIISFAYIRIWSKLRNHVSPVGRNDRHHR 253

  Fly   298 QVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQD--DYNAFWHVLRIVAYCMSFANSC 360
                |||....::..||:|.:.:||:|.|.|......:..|  |:...:.|..|||.|.:|
Zfish   254 ----RRKTTKMLVTMVVVFAVSWLPFHAFQLAIDIDHSVLDMKDFRLLYTVFHIVAMCSTF---- 310

  Fly   361 ANPVALYFVSGAFRKHFNRYLFCR 384
            |||:...:::..:|..|.....|:
Zfish   311 ANPLLYGWMNRNYRSAFVAVFRCK 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	83/310 (27%)
		TM helix 1	83..109	CDD:320593	7/25 (28%)
		TM helix 2	116..142	CDD:320593	10/25 (40%)
		TM helix 3	154..184	CDD:320593	7/29 (24%)
		TM helix 4	201..221	CDD:320593	4/23 (17%)
		TM helix 5	252..277	CDD:320593	8/24 (33%)
		TM helix 6	300..330	CDD:320593	11/29 (38%)
		TM helix 7	345..370	CDD:320593	9/24 (38%)
npy2rl	NP_001314731.1	7tm_GPCRs	45..327	CDD:475119	83/322 (26%)
		TM helix 1	47..71	CDD:410628	7/23 (30%)
		TM helix 2	80..102	CDD:410628	10/21 (48%)
		TM helix 3	118..140	CDD:410628	4/21 (19%)
		TM helix 4	161..177	CDD:410628	1/15 (7%)
		TM helix 5	209..232	CDD:410628	8/26 (31%)
		TM helix 6	258..280	CDD:410628	7/21 (33%)
		TM helix 7	295..320	CDD:410628	9/28 (32%)