Protein Alignment CCHa1-R and Kiss1r

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_076482.2
• Gene: Kiss1r / 78976
• RGDID: 70930
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 413
• Identity: 114/413 - (27%)
• Similarity: 182/413 - (44%)
• Gaps: 73/413 - (17%)

  Fly    78 RP-ETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTV 141
            || :.::||:.||.:.::|::||..:|.|....:.|:.|.|.||.:||..|:..::..||..:.:
  Rat    38 RPLDAWLVPLFFAALMLLGLVGNSLVIFVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALL 102

  Fly   142 YTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLAT 206
            |.:..|..|.|:|....:::.||:..:..||||:|.||::..|.|||..|     ||..|:.|..
  Rat   103 YPLPTWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALH-----RRTPRLALTV 162

  Fly   207 AVSIWLLAILCGLPALIGSNLK---HLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPL 268
            ::|||:.:.....|.|....|.   |...:|       .:|..   ...::..|.:.|..|.:||
  Rat   163 SLSIWVGSAAVSAPVLALHRLSPGPHTYCSE-------AFPSR---ALERAFALYNLLALYLLPL 217

  Fly   269 VVIAVFYVLIALHLMYSASVP----GEIQGAVRQVRA---RRKVAVTVLAFVVIFGICFLPYHVF 326
            :.....|..:..||..:|..|    |.:||.:...||   |.||:..|.|.|::|..|:.|..:|
  Rat   218 LATCACYGAMLRHLGRAAVRPAPTDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLF 282

  Fly   327 FLWFYFWPTAQDDYNAFWH-------VLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCR 384
            .:.....|:..      ||       .|:|.|:|||::||..||:...|:...||:.|.|...|
  Rat   283 LVLQALGPSGA------WHPRSYAAYALKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPC- 340

  Fly   385 GASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTLPNGGNQNGAN 449
               |.:::|..|.:  .|.|.:          :.||...|     |.........|..||
  Rat   341 ---GPQRQRRPHAS--AHSDRA----------APHSVPHS-----RAAHPVRVRTPEPGN----- 380

  Fly   450 ISAVELALPVLQAPGHNEAHAPP 472
                    ||:::|...:.|..|
  Rat   381 --------PVVRSPSVQDEHTAP 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	92/311 (30%)
		TM helix 1	83..109	CDD:320593	9/25 (36%)
		TM helix 2	116..142	CDD:320593	8/25 (32%)
		TM helix 3	154..184	CDD:320593	10/29 (34%)
		TM helix 4	201..221	CDD:320593	5/19 (26%)
		TM helix 5	252..277	CDD:320593	6/24 (25%)
		TM helix 6	300..330	CDD:320593	12/32 (38%)
		TM helix 7	345..370	CDD:320593	12/31 (39%)
Kiss1r	NP_076482.2	7tmA_KiSS1R	43..334	CDD:320223	92/311 (30%)
		TM helix 1	44..70	CDD:320223	9/25 (36%)
		TM helix 2	77..103	CDD:320223	8/25 (32%)
		TM helix 3	115..145	CDD:320223	10/29 (34%)
		TM helix 4	157..177	CDD:320223	5/19 (26%)
		TM helix 5	201..230	CDD:320223	6/28 (21%)
		TM helix 6	256..286	CDD:320223	10/29 (34%)
		TM helix 7	302..327	CDD:320223	11/24 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	346..396		16/80 (20%)