Protein Alignment CCHa1-R and gpr37l1

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001072523.1
• Gene: gpr37l1 / 779978
• XenbaseID: XB-GENE-982680
• Length: 451
• Species: Xenopus tropicalis
• Alignment Length: 439
• Identity: 86/439 - (19%)
• Similarity: 162/439 - (36%)
• Gaps: 114/439 - (25%)

  Fly    25 PTALPPMPNVTETLWDLAMVVSQSTQW-PLLDTGSSENFSELVTTETPYVPYGRRP-ETYIVPIL 87
            |..:.|.|:.|..|..:....:.::.| |.|              :.|..|.|... ..|.|.:|
 Frog    69 PRLIHPPPSGTPLLNQILNDTALTSTWHPQL--------------QNPLYPLGESSLSAYGVLLL 119

  Fly    88 FALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSF 152
            ..::|.||::||.:::.:......:::..::.:..|||.|.:::...:|:............|..
 Frog   120 SLVVFAVGIIGNLSVMCIVWHSLYLKSAWDSILAGLALWDFMLLFFCLPVVVFQEITRRRLLGVV 184

  Fly   153 LCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATR--MTLATAVSIWLLAI 215
            .|.:..:|:..|:|||.|:|.||..||:.:|..|      ....|...|  ..|.....|||.::
 Frog   185 SCRVVPYMEVTSLGVSTFSLCALGIDRFQSITSP------QMSPRPVERCQSILGKLAVIWLGSL 243

  Fly   216 LCGLPALI----------GSNL----------KHLGINEKSIVICYPYPEEWGINYAKSMVLLHF 260
            :..||.::          ||.:          .:|.....|:|:.|.:...|           .|
 Frog   244 ILALPEILLWQFTQEQSPGSGMVIDTCVMLPAPNLPPVLHSLVLTYQHARMW-----------WF 297

  Fly   261 L-VYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYH 324
            | .|:.:|| :..:..:|:.|.::.::.       .::..:.:|:::..|.:...::|:|.||.:
 Frog   298 LGCYFCLPL-LFTITSLLVTLRIVGTSK-------DIKYGQCQRQLSWIVASLATVYGVCTLPEN 354

  Fly   325 V--FFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGAS 387
            |  ..:.:......:|       :|.::.....|......||.|..:|
 Frog   355 VTNVIITYTNLDVPKD-------LLSLITQFFLFLKCAVTPVLLLCLS----------------- 395

  Fly   388 GRRKKRGQH--DTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQET 434
               |:.||.  |..|                   .|.:..|||...|:|
 Frog   396 ---KQLGQAFLDCCC-------------------CCCEEAIRSDSKQQT 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	64/319 (20%)
		TM helix 1	83..109	CDD:320593	7/25 (28%)
		TM helix 2	116..142	CDD:320593	5/25 (20%)
		TM helix 3	154..184	CDD:320593	12/29 (41%)
		TM helix 4	201..221	CDD:320593	6/21 (29%)
		TM helix 5	252..277	CDD:320593	5/25 (20%)
		TM helix 6	300..330	CDD:320593	7/31 (23%)
		TM helix 7	345..370	CDD:320593	5/24 (21%)
gpr37l1	NP_001072523.1	7tm_GPCRs	114..402	CDD:475119	67/339 (20%)
		TM helix 1	116..140	CDD:320254	7/23 (30%)
		TM helix 2	149..171	CDD:320254	5/21 (24%)
		TM helix 3	187..209	CDD:320254	9/21 (43%)
		TM helix 4	233..249	CDD:320254	4/15 (27%)
		TM helix 5	291..314	CDD:320254	6/34 (18%)
		TM helix 6	336..358	CDD:320254	6/21 (29%)
		TM helix 7	370..395	CDD:320254	6/31 (19%)