Protein Alignment CCHa1-R and gpr83.2

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001072505.1
• Gene: gpr83.2 / 779960
• XenbaseID: XB-GENE-993677
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 417
• Identity: 101/417 - (24%)
• Similarity: 188/417 - (45%)
• Gaps: 68/417 - (16%)

  Fly    55 DTGSSENFSELVTTETPYVPYGRRPET-YIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNT 118
            |.|..||       :|.|....:.... .::.:.:::|.|:.:.||..:..|.:...:|::..:.
 Frog    49 DIGDFEN-------DTKYEAESQSSTVKALLIVAYSVIIVISLFGNILVCHVVIKNSRMQSATSL 106

  Fly   119 YILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAI 183
            :|::||:||:::.:...|.....:....|.:|..:|.:|.|::..|:.|||.||.|::.||:..|
 Frog   107 FIVNLAVADIMITLLNTPFTLVRFVSSTWVFGKLMCHVSRFVQYCSVHVSVLTLMAIALDRHQVI 171

  Fly   184 VDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVIC---YPYPE 245
            :.||:.       |.:|...:...:.||.:|....||..:...|:...|.....::|   :|||.
 Frog   172 MHPLKP-------RMSTVKGIICIIVIWFMASGFSLPHAVYQKLEQFFIGNTVRMVCLPSFPYPA 229

  Fly   246 E--WGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRA-RRKVAV 307
            :  |     |.:.|..|::.|.:||:||::.|..:|..|....:: |:|  .:.|..| |||..:
 Frog   230 DLFW-----KYLDLATFVLLYVLPLIVISITYTTVAKKLWLRNAI-GDI--TMEQYYAHRRKKKM 286

  Fly   308 T---VLAFVVIFGICFLPYHVFFLWFYFWPTAQDD--YNAF-WHVLRIVAYCMSFANSCANPVAL 366
            |   ::..||:|.:|:.|.:.:.:.......:.::  |.|| |       :.||  ::|.||...
 Frog   287 TLKMLMLVVVVFAVCWFPLNCYLVLMSSKVISSNNAIYFAFHW-------FAMS--STCYNPFIY 342

  Fly   367 YFVSGAFRKHFNRYL-FCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCR 430
            .:::.:||......| .||    ||.....|         .|.|.:.   |.||:..:    :|.
 Frog   343 CWLNESFRSELKALLCVCR----RRSPAQSH---------PLQSVSP---QFRHAWTE----NCH 387

  Fly   431 LQETTITTLPNGG---NQNGANISAVE 454
            .::.:.:......   |....:||:||
 Frog   388 FKQGSSSQAAGSATNVNSGRTDISSVE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	78/306 (25%)
		TM helix 1	83..109	CDD:320593	5/25 (20%)
		TM helix 2	116..142	CDD:320593	6/25 (24%)
		TM helix 3	154..184	CDD:320593	12/29 (41%)
		TM helix 4	201..221	CDD:320593	4/19 (21%)
		TM helix 5	252..277	CDD:320593	9/24 (38%)
		TM helix 6	300..330	CDD:320593	10/33 (30%)
		TM helix 7	345..370	CDD:320593	5/24 (21%)
gpr83.2	NP_001072505.1	7tmA_GPR83	70..353	CDD:320511	78/306 (25%)
		TM helix 1	71..97	CDD:320511	5/25 (20%)
		TM helix 2	104..129	CDD:320511	6/24 (25%)
		TM helix 3	142..172	CDD:320511	12/29 (41%)
		TM helix 4	183..204	CDD:320511	5/20 (25%)
		TM helix 5	233..262	CDD:320511	11/33 (33%)
		TM helix 6	282..312	CDD:320511	8/29 (28%)
		TM helix 7	321..346	CDD:320511	9/33 (27%)