Protein Alignment CCHa1-R and TACR2

DIOPT Version :9

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001048.2
• Gene: TACR2 / 6865
• HGNCID: 11527
• Length: 398
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 104/415 - (25%)
• Similarity: 184/415 - (44%)
• Gaps: 62/415 - (14%)

  Fly    54 LDTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNT 118
            :.:|...|.:.:.....|..........|:..:|      |.|.||..:|.:.|:.|:||.|.|.
Human    12 ISSGPESNTTGITAFSMPSWQLALWATAYLALVL------VAVTGNAIVIWIILAHRRMRTVTNY 70

  Fly   119 YILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAI 183
            :|::||||||.:............:...|.:|...|.........::.||::::||::.|||.||
Human    71 FIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAI 135

  Fly   184 VDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWG 248
            |.|.:.       |.:...|.|....|||:|:....|....|.:.   :::.:......:||:.|
Human   136 VHPFQP-------RLSAPSTKAVIAGIWLVALALASPQCFYSTVT---MDQGATKCVVAWPEDSG 190

  Fly   249 INYAKSMVLLHFLV---YYAIPLVVIAVFYVLIALHLMYSASVPG-EIQGA-VRQVRARRKVAVT 308
               .|:::|.|.:|   .|.:||.|:.|.|.:|.|.| :..:||| :..|| :|.::|.:|...|
Human   191 ---GKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTL-WRRAVPGHQAHGANLRHLQAMKKFVKT 251

  Fly   309 VLAFVVIFGICFLPYHVFFLWFYFWPTAQDDY-NAFWHVLRIVAYCMSFANSCANPVALYFVSGA 372
            ::..|:.|.||:||||::|:...|   .:|.| :.|...:.:..:.::.:::..||:....::..
Human   252 MVLVVLTFAICWLPYHLYFILGSF---QEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHR 313

  Fly   373 FRKHFNRYLF--CRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETT 435
            ||..| |..|  |...:..::.:           ..||.|.|         ..:.:..|..:||.
Human   314 FRSGF-RLAFRCCPWVTPTKEDK-----------LELTPTTS---------LSTRVNRCHTKETL 357

  Fly   436 I---TTLPN-------GGNQNGANI 450
            .   .|.|:       |..|:|:.:
Human   358 FMAGDTAPSEATSGEAGRPQDGSGL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	32/99 (32%)
		7tm_1	98..364	CDD:278431	78/271 (29%)
TACR2	NP_001048.2	7tm_4	42..>168	CDD:304433	41/138 (30%)
		7tm_1	50..307	CDD:278431	79/273 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4219
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810