Protein Alignment CCHa1-R and SSTR5

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001044.1
• Gene: SSTR5 / 6755
• HGNCID: 11334
• Length: 364
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 110/353 - (31%)
• Similarity: 173/353 - (49%)
• Gaps: 39/353 - (11%)

  Fly    46 SQSTQWPLLDTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVR 110
            :.:..|.....|::....:..|...|....|.|  ..:||:|:.|:...|:.||..:|.|.|...
Human     7 ASTPSWNASSPGAASGGGDNRTLVGPAPSAGAR--AVLVPVLYLLVCAAGLGGNTLVIYVVLRFA 69

  Fly   111 QMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTAL 175
            :|:.|.|.|||:||:||:|.:: .:|..:|.....:||:|..||.|...:..|:...|||.||.:
Human    70 KMKTVTNIYILNLAVADVLYML-GLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVM 133

  Fly   176 SGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVIC 240
            |.|||.|:|.||    :....||.....||:|.: |:|::...||.|:.::::..|....|
Human   134 SVDRYLAVVHPL----SSARWRRPRVAKLASAAA-WVLSLCMSLPLLVFADVQEGGTCNAS---- 189

  Fly   241 YPYPEE---WGINYAKSMVLLHFLVYYAI-----PLVVIAVFYVLIALHLMYSASVPGEIQGAVR 297
              :||.   ||         ..|::|.|:     ||:||.:.|:||.:    .....|...|.||
Human   190 --WPEPVGLWG---------AVFIIYTAVLGFFAPLLVICLCYLLIVV----KVRAAGVRVGCVR 239

  Fly   298 QVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCAN 362
            : |:.|||...||..|::|..|:||:....:........|:..:|..:...::   :|:||||||
Human   240 R-RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVI---LSYANSCAN 300

  Fly   363 PVALYFVSGAFRKHFNRYLFCRGASGRR 390
            ||...|:|..||:.|.:.|..|..||.:
Human   301 PVLYGFLSDNFRQSFQKVLCLRKGSGAK 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	99/302 (33%)
		TM helix 1	83..109	CDD:320593	10/25 (40%)
		TM helix 2	116..142	CDD:320593	11/25 (44%)
		TM helix 3	154..184	CDD:320593	13/29 (45%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	8/29 (28%)
		TM helix 6	300..330	CDD:320593	11/29 (38%)
		TM helix 7	345..370	CDD:320593	10/24 (42%)
SSTR5	NP_001044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		2/12 (17%)
		7tmA_SSTR5	51..315	CDD:320640	95/292 (33%)
		TM helix 2	75..101	CDD:320640	11/26 (42%)
		TM helix 3	112..142	CDD:320640	13/29 (45%)
		TM helix 4	154..176	CDD:320640	7/22 (32%)
		TM helix 5	198..227	CDD:320640	11/41 (27%)
		TM helix 6	241..271	CDD:320640	11/29 (38%)
		TM helix 7	283..308	CDD:320640	11/27 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..364		0/2 (0%)