Protein Alignment CCHa1-R and grpr

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_695673.2
• Gene: grpr / 567289
• ZFINID: ZDB-GENE-081015-4
• Length: 376
• Species: Danio rerio
• Alignment Length: 391
• Identity: 138/391 - (35%)
• Similarity: 213/391 - (54%)
• Gaps: 43/391 - (10%)

  Fly    45 VSQSTQWPLL----DTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVV 105
            :|.:|..|::    |:....|.|  ...|.|::..|     .|:..::||:...|::||.|||..
Zfish     1 MSDATLTPVVKFLGDSPERSNTS--AVPEHPHLHSG-----IIIATVYALLITAGLIGNVTLIRT 58

  Fly   106 FLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVF 170
            |..|:.||||||.::.||||.|:|:::|..|:.::.:..:.|.:|...|.|..|::..|:|||||
Zfish    59 FCIVKSMRNVPNLFMSSLALGDVLLLVTCAPVDASKFLADEWLFGRMGCKLIPFIQLTSVGVSVF 123

  Fly   171 TLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLK--HLGIN 233
            |||||:.|||.|||.|:     .....:|:......|.|||:|:::..:|..:.|:|.  |:...
Zfish   124 TLTALAADRYKAIVKPM-----DIQSSKASLKVCLRAASIWMLSMVLAIPEAVFSDLHTFHIPQT 183

  Fly   234 EKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSA-SVPGEIQGAV- 296
            .::...|.|||.. |..:.|...:..||:.|.|||.:|:|:|:.||..|:.|| ::|  ::|..
Zfish   184 NETFKTCAPYPHA-GDLHPKIHSMASFLILYIIPLFIISVYYIFIARSLIQSANNMP--VEGNTH 245

  Fly   297 --RQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANS 359
              |||.:|.::|.|||.||.:|.||:||.||.:|:..:..|..|...|.: :..:.|..::|.||
Zfish   246 IRRQVESRMRLAKTVLVFVGLFAICWLPNHVIYLYRSYHYTEVDTSMAHF-IASVCARILAFTNS 309

  Fly   360 CANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQS 424
            |.||.|||.:|.:|||.||:.|.|...|                 .||.|.:|:|..:|.|..:|
Zfish   310 CVNPFALYLLSKSFRKQFNKQLCCCCPS-----------------ISLRSQSSRRHNTRLSSLKS 357

  Fly   425 T 425
            |
Zfish   358 T 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	115/300 (38%)
		TM helix 1	83..109	CDD:320593	10/25 (40%)
		TM helix 2	116..142	CDD:320593	10/25 (40%)
		TM helix 3	154..184	CDD:320593	18/29 (62%)
		TM helix 4	201..221	CDD:320593	5/19 (26%)
		TM helix 5	252..277	CDD:320593	10/24 (42%)
		TM helix 6	300..330	CDD:320593	15/29 (52%)
		TM helix 7	345..370	CDD:320593	10/24 (42%)
grpr	XP_695673.2	7tm_GPCRs	37..327	CDD:475119	114/298 (38%)
		TM helix 1	37..61	CDD:410628	9/23 (39%)
		TM helix 2	70..92	CDD:410628	9/21 (43%)
		TM helix 3	108..130	CDD:410628	13/21 (62%)
		TM helix 4	153..169	CDD:410628	5/15 (33%)
		TM helix 5	202..225	CDD:410628	9/22 (41%)
		TM helix 6	257..279	CDD:410628	13/21 (62%)
		TM helix 7	295..320	CDD:410628	10/25 (40%)