Protein Alignment CCHa1-R and npffr2a

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001098579.1
• Gene: npffr2a / 560955
• ZFINID: ZDB-GENE-060526-183
• Length: 422
• Species: Danio rerio
• Alignment Length: 459
• Identity: 123/459 - (26%)
• Similarity: 207/459 - (45%)
• Gaps: 80/459 - (17%)

  Fly    34 VTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVPYG-RRPETYIVPIL-FALIFVVGV 96
            :.|:| ||.:.:.....|..:: ||||.|  |......||.|. .:|....|.|: :.|||:|.:
Zfish     1 MNESL-DLNITLVDDGNWTFIN-GSSEFF--LPLNNITYVGYYLHQPSVAAVFIVSYLLIFLVCM 61

  Fly    97 LGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMK 161
            :|||.:..:.|..:.||.|.|.:||:||::||||.|..:|.......:..||:||.:|.:|..::
Zfish    62 IGNGVVCFIVLRSKNMRTVTNLFILNLAISDLLVGIFCMPTTLLDNIITGWPFGSMVCKMSGMVQ 126

  Fly   162 DVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATA----VSIWLLA--ILCGLP 220
            .:|:..|||||.|::.||:..||.|.::           ::|::||    |.||:||  |:|...
Zfish   127 GISVSASVFTLVAIAVDRFRCIVYPFKQ-----------KLTISTATFIIVIIWVLAVSIMCPSG 180

  Fly   221 ALI----GSNLKHLGINEKSIVICYPYPEEW-GINYAKSMVLLHFLVYYAIPLVVIAVFYVLIAL 280
            .::    ..|::....|.:|... |...|.| .....|....:.|...|..||.:|.:.|..|.:
Zfish   181 VMLQVTKEQNIRVFRGNNRSSPF-YWCRENWPNQEMRKIYTTVLFANIYLAPLSLIVIMYARIGI 244

  Fly   281 HLMYSASVPGEIQGAVRQ---VRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDY-N 341
            .|..:|...|...|...:   .:.:::|...:|...::|.:.:||     ||.....|   || .
Zfish   245 TLFKTAMPAGGKHGHDNRHSVSKKKQRVIKMLLIVALLFILSWLP-----LWTLMMLT---DYVK 301

  Fly   342 AFWHVLRIV-------AYCMSFANSCANPVALYFVSGAFRKHFN---RYLFCRGASGRRKKRGQH 396
            ...|..|::       |:.::|.||..||:...|.:..||:.|.   ::..|       ...|||
Zfish   302 LTEHQYRVINIYIYPFAHWLAFFNSSVNPIIYGFFNENFRRGFQAIFKFGLC-------PVGGQH 359

  Fly   397 DTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETT----ITTLPNGGNQNGANISAVELAL 457
            .|:            |.|.|.      ::::...||.:|    :.:|.|..::...:|:..:|.:
Zfish   360 RTY------------SHRVQG------NSVQPVNLQPSTEPISLNSLENNSSRRMNHINEQDLVM 406

  Fly   458 PVLQ 461
            ..|:
Zfish   407 EDLE 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	91/317 (29%)
		TM helix 1	83..109	CDD:320593	10/26 (38%)
		TM helix 2	116..142	CDD:320593	11/25 (44%)
		TM helix 3	154..184	CDD:320593	11/29 (38%)
		TM helix 4	201..221	CDD:320593	10/25 (40%)
		TM helix 5	252..277	CDD:320593	7/24 (29%)
		TM helix 6	300..330	CDD:320593	6/29 (21%)
		TM helix 7	345..370	CDD:320593	9/31 (29%)
npffr2a	NP_001098579.1	7tmA_NPFFR2	47..344	CDD:320646	91/316 (29%)
		TM helix 1	48..74	CDD:320646	10/25 (40%)
		TM helix 2	81..107	CDD:320646	11/25 (44%)
		TM helix 3	119..149	CDD:320646	11/29 (38%)
		TM helix 4	160..181	CDD:320646	9/20 (45%)
		TM helix 5	216..245	CDD:320646	8/28 (29%)
		TM helix 6	267..297	CDD:320646	7/34 (21%)
		TM helix 7	312..337	CDD:320646	7/24 (29%)