Protein Alignment CCHa1-R and tacr3a

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001243567.1
• Gene: tacr3a / 555482
• ZFINID: ZDB-GENE-090312-106
• Length: 399
• Species: Danio rerio
• Alignment Length: 415
• Identity: 107/415 - (25%)
• Similarity: 173/415 - (41%)
• Gaps: 90/415 - (21%)

  Fly    59 SENFSELVTTETPYVPYGRRPETYIVP--------ILFALIFVVGVLGNGTLIVVFLSVRQMRNV 115
            |:|.|.|.         |.....::.|        :.::.|..:.|.||..::.:.|:.::||.|
Zfish     4 SQNGSNLT---------GNFTNQFVQPPWRVALWSVAYSSILAIAVFGNLIVMWIILAHKRMRTV 59

  Fly   116 PNTYILSLALADL-LVIITTVPLASTVY-TVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGD 178
            .|.::|:||.:|. :....|  |.:.|| |...|.:|...|....|....|:..|:::::|::.|
Zfish    60 TNYFLLNLAFSDASMAAFNT--LINFVYATHGDWYFGEAYCKFHNFFPVTSVFASIYSMSAIAVD 122

  Fly   179 RYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICY-- 241
            ||.||:.||:.       |.:...|....|.||:||::...|....|.:|.|    ....:||
Zfish   123 RYMAIIHPLKP-------RLSATATKVIIVCIWVLAVVLAFPLCFFSTIKKL----PKRTLCYVA 176

  Fly   242 -PYPEEWGINYAKSMVLLHFLV---YYAIPLVVIAVFYVLIALHLMYSASVPGE----IQGAVRQ 298
             |.|.|....|       |.:|   .|.:||||:.:.|.::.|.| :...:||:    .||   |
Zfish   177 WPRPSEDPFMY-------HIIVAMLVYVLPLVVMGINYTIVGLTL-WGGEIPGDSSDNYQG---Q 230

  Fly   299 VRARRKVAVTVLAFVVIFGICFLPYHVFFL------WFYFWPTAQDDY-NAFWHVLRIVAYCMSF 356
            :||:|||...::..||.|..|:|||||:||      ....|...|..| :..|         ::.
Zfish   231 LRAKRKVVKMMIIVVVTFAFCWLPYHVYFLVTGLNKQLARWKFIQQIYLSIMW---------LAM 286

  Fly   357 ANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSC 421
            :::..||:....::..||..|.|..                .:|.....|.......|.......
Zfish   287 SSTMYNPIIYCCLNSRFRAGFKRVF----------------RWCPFVQVSDYDELELRAMRHKVA 335

  Fly   422 YQSTIRSCRLQETTITTL-----PN 441
            .||::.:....|||:.|:     ||
Zfish   336 RQSSMYTMSRMETTVVTVCDPSEPN 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	89/321 (28%)
		TM helix 1	83..109	CDD:320593	6/33 (18%)
		TM helix 2	116..142	CDD:320593	7/26 (27%)
		TM helix 3	154..184	CDD:320593	9/29 (31%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	8/27 (30%)
		TM helix 6	300..330	CDD:320593	16/35 (46%)
		TM helix 7	345..370	CDD:320593	2/24 (8%)
tacr3a	NP_001243567.1	7tm_GPCRs	26..307	CDD:475119	88/313 (28%)
		TM helix 1	28..52	CDD:320669	4/23 (17%)
		TM helix 2	61..83	CDD:320669	7/23 (30%)
		TM helix 3	99..121	CDD:320669	4/21 (19%)
		TM helix 4	142..158	CDD:320669	5/15 (33%)
		TM helix 5	185..208	CDD:320669	8/29 (28%)
		TM helix 6	238..260	CDD:320669	9/21 (43%)
		TM helix 7	275..300	CDD:320669	5/33 (15%)