Protein Alignment CCHa1-R and OPRD1

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_000902.3
• Gene: OPRD1 / 4985
• HGNCID: 8153
• Length: 372
• Species: Homo sapiens
• Alignment Length: 385
• Identity: 106/385 - (27%)
• Similarity: 171/385 - (44%)
• Gaps: 67/385 - (17%)

  Fly    74 PYGRRPETYI-----VPILFALIFVVGVLGNGTLIVVFLSVR--QMRNVPNTYILSLALADLLVI 131
            |.|.|..:.:     :..|::.:..||:|||  ::|:|..||  :|:...|.||.:|||||.|.
Human    37 PPGARSASSLALAIAITALYSAVCAVGLLGN--VLVMFGIVRYTKMKTATNIYIFNLALADALA- 98

  Fly   132 ITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGG 196
            .:|:|..|..|.:|.||:|..||.....:...::..|:||||.:|.|||.|:..|::....
Human    99 TSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDF---- 159

  Fly   197 RRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVIC---YPYPEEWGINYAKSMVLL 258
            |...:..|.. :.||:||...|:|.::.:..:    .....|:|   :|.|..:.....|..|
Human   160 RTPAKAKLIN-ICIWVLASGVGVPIMVMAVTR----PRDGAVVCMLQFPSPSWYWDTVTKICV-- 217

  Fly   259 HFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPY 323
             ||..:.:|:::|.|.|.|:.|.|. |..:   :.|:..:.|:.|::...||..|..|.:|:.|.
Human   218 -FLFAFVVPILIITVCYGLMLLRLR-SVRL---LSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI 277

  Fly   324 HVFFLWFYFWPTAQDDYN-----AFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFC 383
            |:|.:   .|.....|..     |..|    :...:.:|||..|||...|:...|::.|.:  .|
Human   278 HIFVI---VWTLVDIDRRDPLVVAALH----LCIALGYANSSLNPVLYAFLDENFKRCFRQ--LC 333

  Fly   384 RGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTLPNGG 443
            |...||             .|.|..|.|      |.:..:..:.:|     |.:..|.||
Human   334 RKPCGR-------------PDPSSFSRA------REATARERVTAC-----TPSDGPGGG 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	88/309 (28%)
		TM helix 1	83..109	CDD:320593	8/30 (27%)
		TM helix 2	116..142	CDD:320593	12/25 (48%)
		TM helix 3	154..184	CDD:320593	11/29 (38%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	8/24 (33%)
		TM helix 6	300..330	CDD:320593	10/29 (34%)
		TM helix 7	345..370	CDD:320593	8/24 (33%)
OPRD1	NP_000902.3	7tmA_Delta_opioid_R	50..329	CDD:320217	88/304 (29%)
		TM helix 1	51..77	CDD:320217	9/27 (33%)
		TM helix 2	84..110	CDD:320217	12/26 (46%)
		TM helix 3	121..151	CDD:320217	11/29 (38%)
		TM helix 4	163..185	CDD:320217	7/22 (32%)
		TM helix 5	209..239	CDD:320217	9/32 (28%)
		TM helix 6	258..284	CDD:320217	8/28 (29%)
		TM helix 7	297..322	CDD:320217	9/28 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		10/41 (24%)