Protein Alignment CCHa1-R and TkR86C

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 142/542 - (26%)
• Similarity: 235/542 - (43%)
• Gaps: 120/542 - (22%)

  Fly     8 METDLAMNIGL------DTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELV 66
            ::|:|.:|..:      :.:....|.|....|.||.:..|:.::...      |...|.|.::..
  Fly     5 VDTELLVNCTILAVRRFELNSIVNTTLLGSLNRTEVVSLLSSIIDNR------DNLESINEAKDF 63

  Fly    67 TTETPYVPYGRRPETYIVP--------ILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSL 123
            .||..: |...||  |.:|        |:|.|:..|.:.|||.::.:....|.||.|.|.::|:|
  Fly    64 LTECLF-PSPTRP--YELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNYFLLNL 125

  Fly   124 ALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLR 188
            ::||||:................||:||..|:::.|:.:|::..|||||.|:|.|||.|||.||:
  Fly   126 SIADLLMSSLNCVFNFIFMLNSDWPFGSIYCTINNFVANVTVSTSVFTLVAISFDRYIAIVHPLK 190

  Fly   189 KFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNL--KHLGINEKSIVICY------PYPE 245
            :    ...||..|:.|   |.||.|:.:...|.|:.|::  ||. .|.||..:|:      .||.
  Fly   191 R----RTSRRKVRIIL---VLIWALSCVLSAPCLLYSSIMTKHY-YNGKSRTVCFMMWPDGRYPT 247

  Fly   246 EWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVL 310
            ... :||.::::|  ::.|.||::|:.:.|.|:...|..|.|:.......:..::::|||....:
  Fly   248 SMA-DYAYNLIIL--VLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMFI 309

  Fly   311 AFVVIFGICFLPYHVFFLWFYF------WPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFV 369
            |.|.||.||:||||:||::.|.      ....|..|..|        |.::.:|:..||:..|::
  Fly   310 AIVSIFAICWLPYHLFFIYAYHNNQVASTKYVQHMYLGF--------YWLAMSNAMVNPLIYYWM 366

  Fly   370 SGAFRKHFNRYLFC-------------------RGASGRRKKRG--------------------- 394
            :..||.:|.|.:.|                   :.:|.|..:.|
  Fly   367 NKRFRMYFQRIICCCCVGLTRHRFDSPKSRLTNKNSSNRHTRGGYTVAHSLPNSSPPTTQTLLAV 431

  Fly   395 ----------QHDTFCMHRDTSLT--STASKRFQSRHSCYQSTIR------SCRLQETTITTLPN 441
                      |......|.....|  |.|..:.|.:.|..::.|:      |||.|.:.....|.
  Fly   432 LAQTLTQPKPQTQLLLSHHSPHPTQPSAAETKSQWKRSTMETQIQQAPVTSSCREQRSAQQQQPP 496

  Fly   442 GGNQNGANISAVELALPVLQAP 463
            |   :|.|.:|||.   :::.|
  Fly   497 G---SGTNRAAVEC---IMERP 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	99/316 (31%)
		TM helix 1	83..109	CDD:320593	8/33 (24%)
		TM helix 2	116..142	CDD:320593	7/25 (28%)
		TM helix 3	154..184	CDD:320593	14/29 (48%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	7/24 (29%)
		TM helix 6	300..330	CDD:320593	15/29 (52%)
		TM helix 7	345..370	CDD:320593	5/24 (21%)
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	97/308 (31%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	7/25 (28%)
		TM helix 3	156..186	CDD:320512	14/29 (48%)
		TM helix 4	197..218	CDD:320512	7/23 (30%)
		TM helix 5	251..280	CDD:320512	9/30 (30%)
		TM helix 6	299..329	CDD:320512	15/29 (52%)
		TM helix 7	342..367	CDD:320512	8/32 (25%)