DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa1-R and Mrgprb4

DIOPT Version :9

Sequence 1:	NP_611241.2	Gene:	CCHa1-R / 37004	FlyBaseID:	FBgn0050106	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001002287.1	Gene:	Mrgprb4 / 404658	RGDID:	738043	Length:	323	Species:	Rattus norvegicus

Alignment Length:	346	Identity:	89/346 - (25%)
Similarity:	147/346 - (42%)	Gaps:	79/346 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VSQSTQ-WPLLDTGSSEN-FSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFL 107
            :|.:|| |.:.:|...|| ::|:::..|.:         ..:..|..:|.|||:.||.| ::..|
  Rat     1 MSPTTQAWSINNTVVKENYYTEILSCITTF---------NTLNFLIVIISVVGMAGNAT-VLWLL 55

  Fly   108 SVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVE---YWPYGSFLCSLSEFMKDVSIGVSV 169
            .....||..:.|:|:||.||.|.:     .|.|||::|   .:....|...|:..|.:...|..:
  Rat    56 GFHMHRNAFSVYVLNLAGADFLYL-----CAQTVYSLECVLQFDNSYFYFLLTILMFNYLAGFCM 115

  Fly   170 FTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSI-WLLAILCGLPALIGSNLKHLGIN 233
              :.|:|.:|..::..|: .:|.     :..|.|.||..:: |..::|..|  |:|.
  Rat   116 --IAAISTERCLSVTWPI-WYHC-----QRPRHTSATVCALFWAFSLLLSL--LLGQ-------- 162

  Fly   234 EKSIVICYPYPEEWGINYAKSMVLLHFLVY--YAIPLVVIAVFYVLIALHLMYSASVPGEIQGAV 296
                          |..:..|.....|..|  :.....:|.:|.||....|...|.:   |.|:.
  Rat   163 --------------GCGFLFSKFDYSFCRYCNFIATAFLIVIFMVLFVSSLALLAKI---ICGSH 210

  Fly   297 R--QVRARRKVAVTVLAFVVI---FGICFLPYHVFFL-WFYFWPTAQDDYNAFWHVLRIVAYCMS 355
            |  ..|....:|:|||.|:..   .|||     ||.| |.:..      .::|::.:..:..|:
  Rat   211 RIPVTRFYVTIALTVLVFIFFGLPIGIC-----VFLLPWIHMM------LSSFFYEMVTLLSCV- 263

  Fly   356 FANSCANPVALYFVSGAFRKH 376
              ||||||: :||..|:.|.|
  Rat   264 --NSCANPI-IYFFVGSIRHH 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	30/102 (29%)
CCHa1-R	NP_611241.2	7tm_1	98..364	CDD:278431	69/277 (25%)
Mrgprb4	NP_001002287.1	7tm_4	38..>201	CDD:304433	49/200 (25%)
		7tm_1	47..272	CDD:278431	70/280 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	298..323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000