DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCHa1-R and Mrgprb5

DIOPT Version :9

Sequence 1:	NP_611241.2	Gene:	CCHa1-R / 37004	FlyBaseID:	FBgn0050106	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001002284.1	Gene:	Mrgprb5 / 404644	RGDID:	738052	Length:	353	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	86/370 - (23%)
Similarity:	140/370 - (37%)	Gaps:	92/370 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVPYGRRPETYI 83
            :|||:..:..|..|.     |.:...|.:...:       :|..|.::|..|
  Rat    26 NTSGKFLSVGPATPG-----WSINNTVVKENYY-------TEKLSCIITFNT------------- 65

  Fly    84 VPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYW- 147
            :..|.|.|.|||..||.| ::..|.....|...:.|:.:||.||.|.:.|     .|||::|..
  Rat    66 LNFLTATISVVGTAGNAT-VLRLLGFHMHRYAFSVYVFNLAGADFLYLCT-----QTVYSLECVL 124

  Fly   148 ----PYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAV 208
                .|..||.::..|    :...::..:.|:|.:|..::..|: .:|.     :..|.|.||..
  Rat   125 QFDNSYFYFLLTILMF----AYLAALCMIPAISTERCLSVTWPI-WYHC-----QRPRHTSATVC 179

  Fly   209 SI-WLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIA 272
            :: |..::|  |..|:|.....| ..:.....|         .|...:.....:|.:.:|.|...
  Rat   180 ALFWAFSLL--LRLLLGQGCGFL-FGKYDYYFC---------RYCSFITTAFLIVLFVVPFVSSL 232

  Fly   273 VFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGI------CFLPYHVFFLWFY 331
            .....|   :..|..:|        ..|....:|||||.| ..||:      ..||..|.|
  Rat   233 AMLTKI---ICGSHRIP--------VTRFYVTIAVTVLVF-TFFGLPVGIISLLLPRIVVF---- 281

  Fly   332 FWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKH 376
                     ...:::.:||.:..| .|.||||: :||:.|:.|.|
  Rat   282 ---------RGVFYIYKIVTFLYS-VNCCANPI-IYFLIGSIRHH 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	29/104 (28%)
CCHa1-R	NP_611241.2	7tm_1	98..364	CDD:278431	63/277 (23%)
Mrgprb5	NP_001002284.1	7tm_1	80..306	CDD:278431	64/280 (23%)
Mrgprb5	NP_001002284.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000