Protein Alignment CCHa1-R and GALR1

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001471.2
• Gene: GALR1 / 2587
• HGNCID: 4132
• Length: 349
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 109/359 - (30%)
• Similarity: 175/359 - (48%)
• Gaps: 49/359 - (13%)

  Fly    75 YGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVR--QMRNVPNTYILSLALADLLVIITTVPL 137
            :|...|.::..::|.|||.:|||||..:|.|....:  :.|:..|.:||:|::|||..::..:|.
Human    27 FGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPF 91

  Fly   138 ASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRM 202
            .:|||.:..|..|:|:|....:...||:.||:|||.|:|.|||.|||...|     ....|.:|.
Human    92 QATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRR-----SSSLRVSRN 151

  Fly   203 TLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEW-GINYAKSMVLLHFLVYYAI 266
            .|.....||.|:|....|......|.|...:.::  .|:   |:| ...:.|:.|:..|:..|.:
Human   152 ALLGVGCIWALSIAMASPVAYHQGLFHPRASNQT--FCW---EQWPDPRHKKAYVVCTFVFGYLL 211

  Fly   267 PLVVIAVFYVLIALHL---MYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFL 328
            ||::|...|..:..||   :.:.|...|        .:::|.|.|||..||:|||.:||:|:..|
Human   212 PLLLICFCYAKVLNHLHKKLKNMSKKSE--------ASKKKTAQTVLVVVVVFGISWLPHHIIHL 268

  Fly   329 W--FYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRK 391
            |  |..:|.....:     :.||.|:|::::||..||:...|:|..|||.:.:...|.
Human   269 WAEFGVFPLTPASF-----LFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCH------- 321

  Fly   392 KRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQST 425
                     :.:|:.|:.|  |..:||.....||
Human   322 ---------IRKDSHLSDT--KESKSRIDTPPST 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	98/302 (32%)
		TM helix 1	83..109	CDD:320593	11/25 (44%)
		TM helix 2	116..142	CDD:320593	9/25 (36%)
		TM helix 3	154..184	CDD:320593	14/29 (48%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	8/24 (33%)
		TM helix 6	300..330	CDD:320593	15/31 (48%)
		TM helix 7	345..370	CDD:320593	9/24 (38%)
GALR1	NP_001471.2	7tmA_Gal1_R	34..314	CDD:320226	98/302 (32%)
		TM helix 1	35..61	CDD:320226	11/25 (44%)
		TM helix 2	70..96	CDD:320226	9/25 (36%)
		TM helix 3	108..138	CDD:320226	14/29 (48%)
		TM helix 4	150..170	CDD:320226	6/19 (32%)
		TM helix 5	197..226	CDD:320226	8/28 (29%)
		TM helix 6	240..270	CDD:320226	14/29 (48%)
		TM helix 7	282..307	CDD:320226	9/29 (31%)