Protein Alignment CCHa1-R and Nmbr

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_036931.1
• Gene: Nmbr / 25264
• RGDID: 3181
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 448
• Identity: 148/448 - (33%)
• Similarity: 228/448 - (50%)
• Gaps: 76/448 - (16%)

  Fly    28 LPP--MPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVP--YGRRPETYI---VP 85
            :||  :||::                  |.|.:||:..|....|..::|  .|...|..|   :|
  Rat     1 MPPRSLPNLS------------------LPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIP 47

  Fly    86 ILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYG 150
            .|:.:|..||:|||..|:.:||:...||:|||.:|.:||..|||:::|.||:.::.|..:.|.:|
  Rat    48 SLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFG 112

  Fly   151 SFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAI 215
            ...|.|...::..|:|||||||||||.|||.|||:|: .....|    ....|...||.||::::
  Rat   113 KLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPM-DMQTSG----VVLWTSLKAVGIWVVSV 172

  Fly   216 LCGLPALIGSNLKHLGINE-KSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIA 279
            |..:|..:.|.:..:|.:: .|...|.|||:...: :.|...:|.||||:.||||:|:::|..||
  Rat   173 LLAVPEAVFSEVARIGSSDNSSFTACIPYPQTDEL-HPKIHSVLIFLVYFLIPLVIISIYYYHIA 236

  Fly   280 LHLMYSA-SVPGEI-QGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYN- 341
            ..|:.|| ::|||. :...:|:..|:::|..||.||..|..|:.|.|:.:|:..|      :|.
  Rat   237 KTLIRSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSF------NYKE 295

  Fly   342 ---AFWH-VLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMH 402
               :..| ::.:||..:||:|||.||.|||.:|.:||||||..|.|          ||
  Rat   296 IDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCC----------GQ------- 343

  Fly   403 RDTSLTSTASKRFQSRHSCY---QSTIRSCRLQETTITTLPNGGNQNGANISAVELAL 457
                      |.:..|.:.|   .|.:|...|:......:.|....|| :.:..|:||
  Rat   344 ----------KSYPERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNG-HSTKQEIAL 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	116/305 (38%)
		TM helix 1	83..109	CDD:320593	12/28 (43%)
		TM helix 2	116..142	CDD:320593	11/25 (44%)
		TM helix 3	154..184	CDD:320593	18/29 (62%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	12/24 (50%)
		TM helix 6	300..330	CDD:320593	11/29 (38%)
		TM helix 7	345..370	CDD:320593	13/25 (52%)
Nmbr	NP_036931.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		8/36 (22%)
		7tm_GPCRs	44..335	CDD:475119	115/302 (38%)
		TM helix 1	46..70	CDD:410628	10/23 (43%)
		TM helix 2	79..101	CDD:410628	10/21 (48%)
		TM helix 3	117..139	CDD:410628	12/21 (57%)
		TM helix 4	162..178	CDD:410628	5/15 (33%)
		TM helix 5	210..233	CDD:410628	11/22 (50%)
		TM helix 6	265..287	CDD:410628	9/21 (43%)
		TM helix 7	303..328	CDD:410628	12/24 (50%)