Protein Alignment CCHa1-R and npr-12

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001293732.1
• Gene: npr-12 / 188742
• WormBaseID: WBGene00020689
• Length: 397
• Species: Caenorhabditis elegans
• Alignment Length: 326
• Identity: 79/326 - (24%)
• Similarity: 142/326 - (43%)
• Gaps: 63/326 - (19%)

  Fly    83 IVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTV--E 145
            ||| ::.|:...|.|.|..:::.|:....:||:.|::|::||.:||::.:.|.|:  |:||.  .
 Worm    44 IVP-MYGLVCSFGALANFIVLLAFVRTANLRNLRNSFIVNLAFSDLILCVVTAPV--TLYTSLNL 105

  Fly   146 YWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSI 210
            :||:|.:.|.....::.|:..||..||..::.||....:.|:|       .|.|....|.....:
 Worm   106 FWPFGDWSCKFLAGVQAVNTFVSSLTLAFIAMDRVLLTLCPVR-------WRLAATAPLLCYGVV 163

  Fly   211 WLLAILCGLP-AL-IGSNLKHLG-------------INEKSIVICYPYPEEWGINYAKSMVLLHF 260
            |:::|:..|| || :.|.|....             .|.:...||....|.|. |...|.....|
 Worm   164 WIISIIVALPYALAVSSKLAPFDPWSDRATPKMLTYCNRQVPEICAEMQEAWD-NAIVSKTTYTF 227

  Fly   261 LV---YYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVR-QVRARRKVAVTVLAFVVI-FGICF 320
            :|   .|.:||..:|..|..|...:...:.|...:....| |::.|.:.|:.:|..:|: :.:|:
 Worm   228 VVLGIQYILPLAALAYAYFQIGSTIQKRSKVSRTVDTTRRMQMQNRNRRALLLLFLLVLTYAVCW 292

  Fly   321 LPYHVFFLWFYFWPTAQDDYNAFWHVLR------------IVAYCMSFANSCANPVALYFVSGAF 373
            .|.:::                  |||.            |..:.:..:::|.||:....|:.:|
 Worm   293 APMNIY------------------HVLNGLEIINYSQNMYIFCHLVGISSTCVNPIVYALVNESF 339

  Fly   374 R 374
            |
 Worm   340 R 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	79/326 (24%)
		TM helix 1	83..109	CDD:320593	8/25 (32%)
		TM helix 2	116..142	CDD:320593	9/25 (36%)
		TM helix 3	154..184	CDD:320593	8/29 (28%)
		TM helix 4	201..221	CDD:320593	5/20 (25%)
		TM helix 5	252..277	CDD:320593	8/27 (30%)
		TM helix 6	300..330	CDD:320593	6/30 (20%)
		TM helix 7	345..370	CDD:320593	7/36 (19%)
npr-12	NP_001293732.1	7tmA_NPYR-like	42..343	CDD:320331	79/326 (24%)
		TM helix 1	43..69	CDD:320331	8/25 (32%)
		TM helix 2	76..101	CDD:320331	9/26 (35%)
		TM helix 3	114..144	CDD:320331	8/29 (28%)
		TM helix 4	155..176	CDD:320331	5/20 (25%)
		TM helix 5	222..251	CDD:320331	8/28 (29%)
		TM helix 6	272..302	CDD:320331	8/47 (17%)
		TM helix 7	311..336	CDD:320331	4/24 (17%)