Protein Alignment CCHa1-R and Oprl1

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001305848.1
• Gene: Oprl1 / 18389
• MGIID: 97440
• Length: 396
• Species: Mus musculus
• Alignment Length: 359
• Identity: 102/359 - (28%)
• Similarity: 172/359 - (47%)
• Gaps: 42/359 - (11%)

  Fly    65 LVTTETPYVPYGRRPETYIVPI--LFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALAD 127
            |..:.:.::|.|.:     |.|  |:..:.:.|:|||..::.|.|...:|:...|.||.:|||||
Mouse    35 LNASHSAFLPLGLK-----VTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALAD 94

  Fly   128 LLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHA 192
            .||:: |:|...|...:.:||:|:.||.....:...::..|.|||||:|.|||.||..|:|....
Mouse    95 TLVLL-TLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDV 158

  Fly   193 HGGGRRATRMTLATAVSIWLLAILCGLP-ALIGSNLKHLGINEKSIVICYPYPEE-WGINYAKSM 255
                 |.:....|..|:||.||.:.|:| |::||  ..:...|...::..|.|:: ||..:|
Mouse   159 -----RTSSKAQAVNVAIWALASVVGVPVAIMGS--AQVEDEEIECLVEIPAPQDYWGPVFA--- 213

  Fly   256 VLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGE--IQGAVRQVRARRKVAVTVLAFVVIFGI 318
             :..||..:.||:::|:|.|.|:...|.      |.  :.|:..:.|..|::...||..|.:|..
Mouse   214 -ICIFLFSFIIPVLIISVCYSLMIRRLR------GVRLLSGSREKDRNLRRITRLVLVVVAVFVG 271

  Fly   319 CFLPYHVFFL--WFYFWPTAQDDYNAFWHVLRIVAYC--MSFANSCANPVALYFVSGAFRKHFNR 379
            |:.|..||.|  .....|.::.       .:.|:.:|  :.:.|||.||:...|:...|:..|.:
Mouse   272 CWTPVQVFVLVQGLGVQPGSET-------AVAILRFCTALGYVNSCLNPILYAFLDENFKACFRK 329

  Fly   380 YLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASK 413
              ||..::..|:.:.......:.:|..|....|:
Mouse   330 --FCCASALHREMQVSDRVRSIAKDVGLGCKTSE 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	92/304 (30%)
		TM helix 1	83..109	CDD:320593	9/27 (33%)
		TM helix 2	116..142	CDD:320593	13/25 (52%)
		TM helix 3	154..184	CDD:320593	12/29 (41%)
		TM helix 4	201..221	CDD:320593	8/20 (40%)
		TM helix 5	252..277	CDD:320593	8/24 (33%)
		TM helix 6	300..330	CDD:320593	11/31 (35%)
		TM helix 7	345..370	CDD:320593	8/26 (31%)
Oprl1	NP_001305848.1	7tmA_NOFQ_opioid_R	49..327	CDD:320220	92/302 (30%)
		TM helix 1	50..76	CDD:320220	8/25 (32%)
		TM helix 2	83..109	CDD:320220	13/26 (50%)
		TM helix 3	120..150	CDD:320220	12/29 (41%)
		TM helix 4	162..184	CDD:320220	8/21 (38%)
		TM helix 5	209..238	CDD:320220	10/32 (31%)
		TM helix 6	253..283	CDD:320220	11/29 (38%)
		TM helix 7	295..320	CDD:320220	8/24 (33%)