Protein Alignment CCHa1-R and npr-3

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_502162.1
• Gene: npr-3 / 182494
• WormBaseID: WBGene00007006
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 87/373 - (23%)
• Similarity: 161/373 - (43%)
• Gaps: 80/373 - (21%)

  Fly    83 IVPILFALIFVVGVLGNGTLIVVFLSVRQMR-NVPNTYILSLALADLLVIITTVPLASTVYTVEY 146
            |..:|:.|::|..::|| ||::..|:..|:. :|...::..||.:|||:.:.::|:.:.......
 Worm    27 IFSLLYLLVWVGAIVGN-TLVLYVLTFNQVSLSVRTVFVGCLAGSDLLMCLFSLPITAISIFSRV 90

  Fly   147 WPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAV--- 208
            |.:.:..|.|....:..:|.||.||||.::.||...|:.|.::.           :....||
 Worm    91 WVFPAIFCKLIGVFQGGTIFVSSFTLTVIALDRCVLILRPNQEI-----------VNFPRAVFIV 144

  Fly   209 -SIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEE-W----------GIN--YAKSMVLLH 259
             .||||.....||..|.|:   :.:.::   ||..:.|| |          ||.  |..|:::|.
 Worm   145 FCIWLLGYSLALPVGIYSD---IAVYDE---ICGTFCEENWPDFNPDTGRSGIRRAYGLSVLVLQ 203

  Fly   260 FLVYYAIPLVVIAVFYVLI--------ALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIF 316
            |    .||.::.::.|.:|        |....::.....|.:...|:.||.|.:.|.|:.||
 Worm   204 F----GIPALISSICYWMISRVMSDQLARRRGHNIRPESETKLVNRKTRANRMMIVMVVGFV--- 261

  Fly   317 GICFLPYHVFFLW-----FYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKH 376
             :.::|::...|:     ...|      |:..:.:..:.|.|    ::..||:...:.:..||:.
 Worm   262 -LAWMPFNAVNLYRDLFGISKW------YSTVFALCHVCAMC----SAVLNPIIYSWFNPQFRQS 315

  Fly   377 FNRYLFCRGASGRR--KKRGQHDTFC---------MHRDTSLTSTASK 413
            ... || :|....|  ||:.|..:..         :.::|.:.||.:|
 Worm   316 ITT-LF-KGTDEARLIKKKPQSTSKMVSYPTNFSEIRKETEIASTKTK 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	76/324 (23%)
		TM helix 1	83..109	CDD:320593	9/25 (36%)
		TM helix 2	116..142	CDD:320593	6/25 (24%)
		TM helix 3	154..184	CDD:320593	11/29 (38%)
		TM helix 4	201..221	CDD:320593	7/23 (30%)
		TM helix 5	252..277	CDD:320593	6/24 (25%)
		TM helix 6	300..330	CDD:320593	9/34 (26%)
		TM helix 7	345..370	CDD:320593	4/24 (17%)
npr-3	NP_502162.1	7tmA_NPYR-like	26..314	CDD:320331	75/322 (23%)
		TM helix 1	27..53	CDD:320331	9/26 (35%)
		TM helix 2	60..85	CDD:320331	6/24 (25%)
		TM helix 3	98..128	CDD:320331	11/29 (38%)
		TM helix 4	139..160	CDD:320331	8/20 (40%)
		TM helix 5	192..221	CDD:320331	8/32 (25%)
		TM helix 6	244..274	CDD:320331	10/33 (30%)
		TM helix 7	284..309	CDD:320331	4/28 (14%)