Protein Alignment CCHa1-R and Npy6r

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_035065.1
• Gene: Npy6r / 18169
• MGIID: 1098590
• Length: 371
• Species: Mus musculus
• Alignment Length: 414
• Identity: 99/414 - (23%)
• Similarity: 188/414 - (45%)
• Gaps: 104/414 - (25%)

  Fly    41 LAMVVSQSTQWPLLDTGSSEN--FSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGN-GTL 102
            :.::.:|.|  |...:|.|.|  |....:.:.|::      ...::.|.:.:|.::|:.|| ..:
Mouse     1 MEVLTNQPT--PNKTSGKSNNSAFFYFESCQPPFL------AILLLLIAYTVILIMGIFGNLSLI 57

  Fly   103 IVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYT-VEYWPYGSFLCSLSEFMKDVSIG 166
            |::|...|:.:||.|..|.:|:|:|:||.:..:|. :.:|| :::|.:|:.:|.|:.:::.||:.
Mouse    58 IIIFKKQREAQNVTNILIANLSLSDILVCVMCIPF-TVIYTLMDHWVFGNTMCKLTSYVQSVSVS 121

  Fly   167 VSVFTLTALSGDRYFAIVDPL----RKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNL 227
            ||:|:|..::.:||..||:|.    |..||:.|           .:.|||:::...:|..:..:|
Mouse   122 VSIFSLVLIAIERYQLIVNPRGWKPRVAHAYWG-----------IILIWLISLTLSIPLFLSYHL 175

  Fly   228 KHLGINEKSI--------VICYPYPEEWGINYAKSMVLLH----FLVYYAIPLVVIAVFYVLIAL 280
            .:...:..|:        |.|.   |.|.   :|...||.    |::.|.:||..|.:.|:.|.|
Mouse   176 TNEPFHNLSLPTDIYTHQVACV---EIWP---SKLNQLLFSTSLFMLQYFVPLGFILICYLKIVL 234

  Fly   281 HLMYSASVPGEIQGAVRQVRAR----------RKVAVTVLAFVVIFGICFLPYHVF---FLWFY- 331
            .|          :...|||..|          ::|.|.:::.||.||.|:||.::|   |.|::
Mouse   235 CL----------RKRTRQVDRRKENKSRLNENKRVNVMLISIVVTFGACWLPLNIFNVIFDWYHE 289

  Fly   332 FWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQH 396
            ...:...|      ::.:|.:.::..::|.||:...|::..|:|.....:              |
Mouse   290 MLMSCHHD------LVFVVCHLIAMVSTCINPLFYGFLNKNFQKDLMMLI--------------H 334

  Fly   397 DTFC--------------MHRDTS 406
            ..:|              ||.|.|
Mouse   335 HCWCGEPQESYENIAMSTMHTDES 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	85/326 (26%)
		TM helix 1	83..109	CDD:320593	7/26 (27%)
		TM helix 2	116..142	CDD:320593	8/25 (32%)
		TM helix 3	154..184	CDD:320593	10/29 (34%)
		TM helix 4	201..221	CDD:320593	3/19 (16%)
		TM helix 5	252..277	CDD:320593	9/28 (32%)
		TM helix 6	300..330	CDD:320593	12/42 (29%)
		TM helix 7	345..370	CDD:320593	5/24 (21%)
Npy6r	NP_035065.1	7tm_GPCRs	42..329	CDD:475119	84/320 (26%)
		TM helix 1	42..63	CDD:320518	6/20 (30%)
		TM helix 2	72..94	CDD:320518	8/22 (36%)
		TM helix 3	110..132	CDD:320518	7/21 (33%)
		TM helix 4	153..169	CDD:320518	4/26 (15%)
		TM helix 5	207..230	CDD:320518	7/22 (32%)
		TM helix 6	260..282	CDD:320518	9/21 (43%)
		TM helix 7	297..322	CDD:320518	6/30 (20%)