Protein Alignment CCHa1-R and npr-28

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_509416.2
• Gene: npr-28 / 181089
• WormBaseID: WBGene00018886
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 489
• Identity: 109/489 - (22%)
• Similarity: 187/489 - (38%)
• Gaps: 125/489 - (25%)

  Fly    43 MVVSQSTQWPLLDTGSSENFSELVTTETPYVPYGRRP-----ETYIVPILFALIFVVGVLGNGTL 102
            |.:|.::   :|.|.|:       ||.:..||....|     |...|.:|::.:.|.||.||..:
 Worm     4 MTISSTS---ILTTVST-------TTSSTIVPSLNDPMEIQFEIMFVMVLYSCLAVTGVGGNCWV 58

  Fly   103 IVVFLSVRQM------RNVP---------NTYILSLALADLLVIITTVPLASTVYTVEYWPYGSF 152
            ::..  ::|:      |:.|         ..|::.|::.||..:| .||:..|...|.::|:|.:
 Worm    59 LIKV--IKQLSGCSSNRSRPYKTVVQSSAYVYLIILSVVDLFSLI-PVPMIVTDVYVNHFPFGLW 120

  Fly   153 LCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILC 217
            .|.||.|.:.::..:|...|||||.|||.|:..|...:      .|.|:.:|......:.::::.
 Worm   121 ACKLSYFCEAINKSLSPMVLTALSVDRYIAVCHPTLYW------LRTTKFSLGVLAVCFSVSLIF 179

  Fly   218 GLPALIGSNLKHLGIN-EKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIA-- 279
            .:|....:.::.:..| ::.|:.|   ..:.|.:.:........:|.|.:||.:|...|:.|.
 Worm   180 IIPVTKKATMQVMKDNTDEEIIKC---AFDHGDSASYVFDTAQAIVCYLVPLFIICAVYLAILHK 241

  Fly   280 --LHLMYSASVPGEIQGAVRQVRARR--KVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDY 340
              :|..:|.      .|....:...|  |.:|.|:||   :.||:.||
 Worm   242 LFIHTRFST------VGKKTSISLGRVVKCSVMVVAF---YFICWTPY----------------- 280

  Fly   341 NAFWHVLRIVAYCMSF--ANSCANPVALYFVSGAFRKHF-----NRYLFCRGASGRRKKRGQHD- 397
               | .:||......|  .||..|...:..|..|..:..     ..|.|     |...|:..|:
 Worm   281 ---W-TMRIHYLVTRFIETNSDGNSTVIDEVVAAVAEEVQDGIETSYFF-----GLISKKRMHNI 336

  Fly   398 ----TFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTLPNGGNQNG----ANISAVE 454
                .:.:|   |||...|......:|.....:||            |.|..||    ||.|..:
 Worm   337 EIALIYILH---SLTYAQSAFNWLFYSFLNRNLRS------------NNGRGNGTRSAANTSVFD 386

  Fly   455 LALPVLQAPGHNEAHAPPSYGFLPLNEIVQQTRS 488
                      :..|.:..:....|:.:.:||..|
 Worm   387 ----------NGNATSTVNTSLTPIWKNIQQMGS 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	73/318 (23%)
		TM helix 1	83..109	CDD:320593	7/25 (28%)
		TM helix 2	116..142	CDD:320593	9/34 (26%)
		TM helix 3	154..184	CDD:320593	14/29 (48%)
		TM helix 4	201..221	CDD:320593	1/19 (5%)
		TM helix 5	252..277	CDD:320593	6/24 (25%)
		TM helix 6	300..330	CDD:320593	10/31 (32%)
		TM helix 7	345..370	CDD:320593	6/26 (23%)
npr-28	NP_509416.2	7tm_classA_rhodopsin-like	41..363	CDD:410626	83/371 (22%)
		TM helix 1	41..72	CDD:410626	7/32 (22%)
		TM helix 2	85..110	CDD:410626	8/25 (32%)
		TM helix 3	122..152	CDD:410626	14/29 (48%)
		TM helix 4	164..183	CDD:410626	1/18 (6%)
		TM helix 5	212..237	CDD:410626	6/24 (25%)
		TM helix 6	257..287	CDD:410626	13/53 (25%)
		TM helix 7	338..363	CDD:410626	6/27 (22%)