Protein Alignment CCHa1-R and npr-25

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_505883.1
• Gene: npr-25 / 179570
• WormBaseID: WBGene00011381
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 98/390 - (25%)
• Similarity: 161/390 - (41%)
• Gaps: 94/390 - (24%)

  Fly    86 ILFALIFVVGVLGN-GTLIVVFLSVRQMRN----VPNT--YILSLALADLLVIITTVPLASTVYT 143
            |.:::.||.|.||| ..|..||...|.:::    :.||  ||::|...||||.: ::|.:.:...
 Worm    25 IPYSICFVFGTLGNTAVLSYVFFITRSLKSSVTALGNTFIYIVALCAVDLLVTV-SIPFSLSYMI 88

  Fly   144 VEYWPYGSFLCSLSEFMKDVSIGV-SVFTLTALSGDRYFAIVDP-LRKFHAHGGGRRATRMT--L 204
            :..|.:|..:|.: .||.::|..: |.|.||||:.|||.||..| :::.|..   |....:|  |
 Worm    89 LNNWVFGELVCKI-HFMLELSNKMCSTFILTALAFDRYMAICHPEIKRIHEM---RHTIYITTIL 149

  Fly   205 ATAVSIWLLAILCGLPALIGSNLKHL--------GINEKSIVI---CYP-YPEEWGINYAKSMVL 257
            || :|::|::     |.::.:.:...        ..||:..||   |.. ...||.:..:.
 Worm   150 AT-LSLFLIS-----PVVLSARVTSFKSGQYFVSAKNERHEVIRQMCIDGMALEWKVWVSA---- 204

  Fly   258 LHFLVYYA--IPLVVIAVFYVLIALHL------MYSASVPGEIQGAVRQVRARRKVAVTVLAFVV 314
              ||:::|  :|..::..||..|.|.|      |..:.:|            .|::.:..:|...
 Worm   205 --FLIFFAFLLPCTLLTYFYAKIVLRLRRQRRTMLQSRIP------------LRRITIYTMAATF 255

  Fly   315 IFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVL--RIVAYCMSFANSCANPVALYFVSGAFRKHF 377
            .:..|.:|         ||  ....||.|..||  ::....|:|.....   .|.|:|.||...|
 Worm   256 FYLSCHIP---------FW--LPQIYNIFSTVLGHKMNPKVMTFTYYSH---LLPFISAAFNWIF 306

  Fly   378 NRYLFCRGASG---------RRKKRGQHDTFCMHRDTSLTSTASKRFQS-----RHSCYQSTIRS 428
            ...|..:...|         |::.:..|:.........|||    :|..     .|...|.:|||
 Worm   307 YARLNSQFKKGLVLVTERMIRKRTKSMHEKGYSEAAVELTS----KFDDVPLMCPHCEAQLSIRS 367

  Fly   429  428
             Worm   368  367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	84/323 (26%)
		TM helix 1	83..109	CDD:320593	10/23 (43%)
		TM helix 2	116..142	CDD:320593	10/27 (37%)
		TM helix 3	154..184	CDD:320593	14/30 (47%)
		TM helix 4	201..221	CDD:320593	6/21 (29%)
		TM helix 5	252..277	CDD:320593	6/26 (23%)
		TM helix 6	300..330	CDD:320593	4/29 (14%)
		TM helix 7	345..370	CDD:320593	6/26 (23%)
npr-25	NP_505883.1	7tm_classA_rhodopsin-like	24..311	CDD:410626	85/328 (26%)
		TM helix 1	24..49	CDD:410626	10/23 (43%)
		TM helix 2	62..87	CDD:410626	9/25 (36%)
		TM helix 3	99..129	CDD:410626	14/30 (47%)
		TM helix 4	141..160	CDD:410626	6/24 (25%)
		TM helix 5	199..224	CDD:410626	6/30 (20%)
		TM helix 6	244..271	CDD:410626	6/37 (16%)
		TM helix 7	286..311	CDD:410626	8/27 (30%)