Protein Alignment CCHa1-R and npr-2

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_501701.2
• Gene: npr-2 / 177790
• WormBaseID: WBGene00003808
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 443
• Identity: 92/443 - (20%)
• Similarity: 181/443 - (40%)
• Gaps: 117/443 - (26%)

  Fly    18 LDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVPYGRRPE-- 80
            ::|..|||..| .:.|:........|:  |..:..|:...||:..:|...|...|:  .:.|:
 Worm     4 VNTRVEAPDLL-ALKNMLRQSDGTRML--QEMRRKLIQLHSSQMINETEETCDRYI--DKHPDMT 63

  Fly    81 ---TYIV--PILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLAST 140
               |.:|  .:|:..||::|:|||..::.:.:..||::.|.|.:||:|..:::|:.:|::|:...
 Worm    64 NEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLPITFI 128

  Fly   141 VYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLA 205
            ....:.|.:.|.:|.|...::..||.||.|:|:|::.|||..:|.|.::       :.::|..:.
 Worm   129 TNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRYNLVVRPHKQ-------KLSSRSAMM 186

  Fly   206 TAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPY-----------------PEEWGI-NYA 252
            .|:.||::                      |:|:|.||                 .|.|.: ...
 Worm   187 IALLIWVI----------------------SVVVCMPYGWYMDVEKLNGLCGEYCSEHWPLAEVR 229

  Fly   253 KSMVLLHFLVYYAIPLVVIAVFYVLIALHLM---------------------------YSASVPG 290
            |....|..:..:..|...:|..|..|...|.                           :..|:..
 Worm   230 KGYTFLVLITQFLFPFATMAFCYYNIFSRLRQRVETKLKKLSERSQLLENSTTCGTTNHIVSINA 294

  Fly   291 E-IQGAVRQ-----VRARRKVAVTVLA-FVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFW---- 344
            | :|..:..     |.|:::...|:|: .|::|...:||::|.        |...:|:.|:
 Worm   295 EAVQNGLENKQRLAVLAQQRRTTTILSCMVLLFAFTWLPHNVV--------TLMIEYDGFFFHSD 351

  Fly   345 ----------HVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGAS 387
                      :::.:.|:.:|...:..||....:::..|::...:.|  ||.|
 Worm   352 ETSATSTDHTYIVSMTAHLISMLTNVTNPFLYAWLNPMFKEMLIKTL--RGGS 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	72/362 (20%)
		TM helix 1	83..109	CDD:320593	8/27 (30%)
		TM helix 2	116..142	CDD:320593	7/25 (28%)
		TM helix 3	154..184	CDD:320593	12/29 (41%)
		TM helix 4	201..221	CDD:320593	4/19 (21%)
		TM helix 5	252..277	CDD:320593	5/24 (21%)
		TM helix 6	300..330	CDD:320593	8/30 (27%)
		TM helix 7	345..370	CDD:320593	4/24 (17%)
npr-2	NP_501701.2	7tmA_NPYR-like	70..394	CDD:320331	72/360 (20%)
		TM helix 1	71..97	CDD:320331	7/25 (28%)
		TM helix 2	104..129	CDD:320331	7/24 (29%)
		TM helix 3	142..172	CDD:320331	12/29 (41%)
		TM helix 4	183..204	CDD:320331	8/42 (19%)
		TM helix 5	229..258	CDD:320331	6/28 (21%)
		TM helix 6	311..341	CDD:320331	9/37 (24%)
		TM helix 7	362..387	CDD:320331	4/24 (17%)