Protein Alignment CCHa1-R and tkr-3

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001343603.1
• Gene: tkr-3 / 177285
• WormBaseID: WBGene00006428
• Length: 400
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 94/399 - (23%)
• Similarity: 169/399 - (42%)
• Gaps: 75/399 - (18%)

  Fly    53 LLDTGSSE-----NFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQM 112
            |.:.|.:|     :|.||    ||.       |..|..:|:|:|..:.|:||..::.:.|...::
 Worm    24 LAEAGEAELSGDDDFYEL----TPV-------ELIIWCMLYAIIAFMAVVGNLLVLYITLFRLRV 77

  Fly   113 RNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSG 177
            |::...:||:|..|||...|..:|........:.|.....||.:..:::.|::.||||||..
 Worm    78 RSITTYFILNLGFADLFTGIFAIPFKFQAALFQEWFLPRSLCRIVPYVETVALTVSVFTLVT--- 139

  Fly   178 DRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLP-ALIGSNLKHLGINEKSIVICY 241
                :.|...|........:.:.|......:.||::|:|..|| .|..:..:....|..|||.|.
 Worm   140 ----SAVHEFRTMFFSKCSQMSPRSAKRCVLLIWIMAVLVSLPHGLFHNTYEFPDDNNTSIVQCL 200

  Fly   242 P-YPEE-WGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRK 304
            | ||:. |...|...:|    ::.|.:|::::...|.:||:.:...:....|:.   ....|.:|
 Worm   201 PVYPDAGWWKTYNVYLV----IIQYFVPMIILDTAYTMIAVKIWSLSQSRVELD---ETKMATQK 258

  Fly   305 VAV---------------TVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIV---A 351
            ::|               |::..|..|.:|:.|...:.|.....|    :.|. |..:.:|   :
 Worm   259 ISVVSMVSPNTQLSQLMRTLIIVVACFSLCWFPLETYLLLNELKP----EING-WKYINLVFFFS 318

  Fly   352 YCMSFANSCANPVALYFVSGAFRKHFN---RYLFCR-GASGRRKKRGQHDTFCMHRDTSLTSTAS 412
            :.::.:|||.||:    :.|.:...:|   |.||.: |...:|:|         ..|.|:  ...
 Worm   319 HWLAMSNSCLNPI----IYGLYNTKYNEEYRRLFRQIGCIWQRQK---------SLDDSM--KPE 368

  Fly   413 KRFQSRHSC 421
            :|:.|.:.|
 Worm   369 RRWNSSNDC 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	73/315 (23%)
		TM helix 1	83..109	CDD:320593	8/25 (32%)
		TM helix 2	116..142	CDD:320593	8/25 (32%)
		TM helix 3	154..184	CDD:320593	8/29 (28%)
		TM helix 4	201..221	CDD:320593	7/20 (35%)
		TM helix 5	252..277	CDD:320593	4/24 (17%)
		TM helix 6	300..330	CDD:320593	9/44 (20%)
		TM helix 7	345..370	CDD:320593	6/27 (22%)
tkr-3	NP_001343603.1	7tm_GPCRs	47..344	CDD:475119	74/319 (23%)
		TM helix 1	49..73	CDD:320515	6/23 (26%)
		TM helix 2	82..104	CDD:320515	8/21 (38%)
		TM helix 3	120..142	CDD:320515	7/28 (25%)
		TM helix 4	163..179	CDD:320515	5/15 (33%)
		TM helix 5	210..233	CDD:320515	4/26 (15%)
		TM helix 6	275..297	CDD:320515	5/21 (24%)
		TM helix 7	312..337	CDD:320515	7/28 (25%)