Protein Alignment CCHa1-R and sNPF-R

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_320180.2
• Gene: sNPF-R / 1280335
• VectorBaseID: AGAMI1_013226
• Length: 575
• Species: Anopheles gambiae
• Alignment Length: 530
• Identity: 126/530 - (23%)
• Similarity: 227/530 - (42%)
• Gaps: 115/530 - (21%)

  Fly     2 IANLVSMETDLAMNIGLDTSGE-APTALPP----MP----NVTETLWDLAMVVSQSTQWPLLDTG 57
            :|:||...|:|.:      :|. .|.||.|    :|    |:|.||.:|....|.:...|   .|
Mosquito    28 MASLVLDHTELPL------AGTIPPAALMPARVLLPSNATNLTLTLEELLRPNSSTVAPP---NG 83

  Fly    58 SSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILS 122
            .::            :.:..:....:..:|::.|||:||.||..:..|....:.|:.|.|.:|.:
Mosquito    84 DND------------IIFSNKLVQIVFCVLYSSIFVLGVFGNVLVCYVVFRNKAMQTVTNLFITN 136

  Fly   123 LALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPL 187
            |||:|:|:.:..||...:...:..|.:|..||......:..|:.:|..|||:::.||:|.|:.|
Mosquito   137 LALSDILLCVLAVPFTPSYTFMRRWVFGKLLCHTVPLAQGCSVYISTLTLTSIAIDRFFVIIYP- 200

  Fly   188 RKFHAHGGGRRATRMTLATAVS----IWLLAILCGLPALIGSNLKHLGINE--------KSIVIC 240
              ||        .||.|:|.::    ||..||:..:|..:...|..:.:|.        .|.:.|
Mosquito   201 --FH--------PRMKLSTCITIIVLIWSFAIMVTMPYGLYMKLHGVALNGTDNATGPLSSAMYC 255

  Fly   241 YP-YPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSA-SVPGEIQGAVRQVRARR 303
            .. :|.|   ...|:..::..::.:.:|.:::|..|:.:::.|...| :.||.......:....|
Mosquito   256 EELWPSE---EMRKTFSIVTSILQFVLPFIIMAFCYICVSIRLNDRARTKPGSKTSRREEADRDR 317

  Fly   304 KVAVT--VLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNA------FWHVLRIVAYCMSFANSC 360
            |....  :::.|.||||.:||.:|..:.        :|:|:      |::::..:|:..:.:::|
Mosquito   318 KKRTNRMLISMVAIFGISWLPLNVVNMC--------NDFNSDINSWRFYNLIFFIAHLTAMSSTC 374

  Fly   361 ANPVALYFVSGAFRKHFNRYLFC--------------RGASG----RRKKRGQHDTFCMHRDTSL 407
            .||....:::..|||.|.:.|.|              |||.|    .|...|.:||.   ::|.:
Mosquito   375 YNPFLYAWLNDNFRKEFKQVLPCFDPSRGRAGTVGGNRGAGGGWRSERTCNGNNDTV---QETLI 436

  Fly   408 TST---ASKRFQSRHSCYQSTIRSCRLQETTITTLPNGGNQNGANISAVELALPVLQAPGHNEAH 469
            .|:   .|.|....|.         :.|:.:.::....|||...:...:...:|.|..|
Mosquito   437 PSSQVLPSSRSSQPHQ---------QPQQLSSSSSQGQGNQPTVDSILLSEVVPPLSLP------ 486

  Fly   470 APPSYG-FLP 478
             ||..| .||
Mosquito   487 -PPLTGAMLP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	79/316 (25%)
		TM helix 1	83..109	CDD:320593	9/25 (36%)
		TM helix 2	116..142	CDD:320593	9/25 (36%)
		TM helix 3	154..184	CDD:320593	9/29 (31%)
		TM helix 4	201..221	CDD:320593	8/23 (35%)
		TM helix 5	252..277	CDD:320593	4/24 (17%)
		TM helix 6	300..330	CDD:320593	10/31 (32%)
		TM helix 7	345..370	CDD:320593	4/24 (17%)
sNPF-R	XP_320180.2	None