Protein Alignment CCHa1-R and Brs3

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_033896.2
• Gene: Brs3 / 12209
• MGIID: 1100501
• Length: 399
• Species: Mus musculus
• Alignment Length: 349
• Identity: 129/349 - (36%)
• Similarity: 196/349 - (56%)
• Gaps: 18/349 - (5%)

  Fly    46 SQSTQWPLLD-TGSSENFSELVTTETPYVPYGRRPETYI-----VPILFALIFVVGVLGNGTLIV 104
            |||....|:. |..:|..|.:|:.:|.:..:.......|     :.|.:|.|..||:|||..||.
Mouse     6 SQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISVGILGNAILIK 70

  Fly   105 VFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSV 169
            ||...:.|:.|||.:|.|||..|||:::|.||:.:|.|..|.|.:|...|.:..|::..|:||||
Mouse    71 VFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSV 135

  Fly   170 FTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINE 234
            ||||.||.|||.|:|.||.:...:     |...|.|.|..||:::::..||..|.||:.......
Mouse   136 FTLTILSADRYKAVVKPLERQPPN-----AILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPN 195

  Fly   235 KSIVI--CYPYP-EEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSA-SVPGEIQG- 294
            :::..  |..|| .|..:....|  ||.|||:|.|||.:|:|:|.|||..|..|. ::|.|.|.
Mouse   196 RNVTFESCNSYPISERLLQEIHS--LLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSH 258

  Fly   295 AVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANS 359
            |.:|:.:|:::|.|||..|.:|.:|:||.|:.:|:..|...:..:::....|:.|.:..::|:||
Mouse   259 ARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNS 323

  Fly   360 CANPVALYFVSGAFRKHFNRYLFC 383
            |.||.|||::|..|::||...|.|
Mouse   324 CVNPFALYWLSKTFQQHFKAQLCC 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	116/304 (38%)
		TM helix 1	83..109	CDD:320593	13/30 (43%)
		TM helix 2	116..142	CDD:320593	13/25 (52%)
		TM helix 3	154..184	CDD:320593	17/29 (59%)
		TM helix 4	201..221	CDD:320593	6/19 (32%)
		TM helix 5	252..277	CDD:320593	13/24 (54%)
		TM helix 6	300..330	CDD:320593	12/29 (41%)
		TM helix 7	345..370	CDD:320593	11/24 (46%)
Brs3	NP_033896.2	7tm_GPCRs	48..341	CDD:475119	115/299 (38%)
		TM helix 1	50..74	CDD:320251	12/23 (52%)
		TM helix 2	83..105	CDD:320251	11/21 (52%)
		TM helix 3	121..143	CDD:320251	11/21 (52%)
		TM helix 4	166..182	CDD:320251	5/15 (33%)
		TM helix 5	215..238	CDD:320251	12/24 (50%)
		TM helix 6	270..292	CDD:320251	10/21 (48%)
		TM helix 7	309..334	CDD:320251	11/24 (46%)