Protein Alignment CCHa1-R and Gpr37

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_476549.1
• Gene: Gpr37 / 117549
• RGDID: 619848
• Length: 603
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 86/381 - (22%)
• Similarity: 156/381 - (40%)
• Gaps: 66/381 - (17%)

  Fly    57 GSSENFSELVTTETPYVP-----YGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVP 116
            |:|.|  ..|..:.|:.|     ||    .|.|..|..:||..|::||..::.:......||::.
  Rat   228 GNSTN--RRVRLKNPFYPLTQESYG----AYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSIS 286

  Fly   117 NTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYF 181
            |:.:.:||..|.|:|...:||.......:.|....|.|.:..:::..|:||:.|||.||..||:
  Rat   287 NSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRF- 350

  Fly   182 AIVDPLRKFHAHGGGRRATRM------------TLATAVSIWLLAILCGLPALIGSNL--KHLGI 232
                           |.||.:            |.|....||:.|:|..||.::...|  :.||.
  Rat   351 ---------------RAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGF 400

  Fly   233 N-----EKSIVICYP-YPEE---WGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASV 288
            :     |:.::...| .|:.   ..:.|..:.:..:|..|:.:| .:..:...|:....:..|.
  Rat   401 SGQAPAERCVIKISPDLPDTIYVLALTYDGARLWWYFGCYFCLP-TLFTITCSLVTARKIRKAE- 463

  Fly   289 PGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYC 353
            ....:|..||:....::..||:|..:::|.|.:|.::..:...:..|......  ..:|.|::..
  Rat   464 KASTRGNKRQIHLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQT--MDLLNIISQF 526

  Fly   354 MSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMHRDTSLTS 409
            :.|..||..||.|:.:...|.:.|.....|....            |:.:.:::||
  Rat   527 LLFFKSCVTPVLLFCLCRPFSRAFMECCCCCCEE------------CIQKSSTVTS 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	73/317 (23%)
		TM helix 1	83..109	CDD:320593	7/25 (28%)
		TM helix 2	116..142	CDD:320593	8/25 (32%)
		TM helix 3	154..184	CDD:320593	11/29 (38%)
		TM helix 4	201..221	CDD:320593	7/31 (23%)
		TM helix 5	252..277	CDD:320593	3/24 (13%)
		TM helix 6	300..330	CDD:320593	6/29 (21%)
		TM helix 7	345..370	CDD:320593	8/24 (33%)
Gpr37	NP_476549.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..232		2/3 (67%)
		7tmA_GPR37	252..550	CDD:320255	73/317 (23%)
		TM helix 1	253..279	CDD:320255	7/25 (28%)
		TM helix 2	286..312	CDD:320255	8/25 (32%)
		TM helix 3	324..354	CDD:320255	12/45 (27%)
		TM helix 4	367..387	CDD:320255	7/19 (37%)
		TM helix 5	429..454	CDD:320255	3/25 (12%)
		TM helix 6	475..505	CDD:320255	6/29 (21%)
		TM helix 7	518..543	CDD:320255	8/24 (33%)