Protein Alignment CCHa1-R and MRGPRX2

DIOPT Version :9

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001290544.1
• Gene: MRGPRX2 / 117194
• HGNCID: 17983
• Length: 330
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 79/318 - (24%)
• Similarity: 135/318 - (42%)
• Gaps: 77/318 - (24%)

  Fly    80 ETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTV 144
            ||.|...|...|.:||::||| .::..|..|..||..:.|:||||.||.|.:...: :...||
Human    29 ETLIPVFLILFIALVGLVGNG-FVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFQI-INCLVY-- 89

  Fly   145 EYWPYGSFLCSLS----EFMKDVS-----IGVSVFTLTALSGDRYFAIVDPL--RKFHAHGGGRR 198
                ..:|.||:|    .|...|.     .|:|:  |:.:|.:|..:::.|:  |       .||
Human    90 ----LSNFFCSISINFPSFFTTVMTCAYLAGLSM--LSTVSTERCLSVLWPIWYR-------CRR 141

  Fly   199 ATRMTLATAVSIWLLAIL--------CGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSM 255
            ...::....|.:|.|::|        ||.....|.:                   .|...:  ..
Human   142 PRHLSAVVCVLLWALSLLLSILEGKFCGFLFSDGDS-------------------GWCQTF--DF 185

  Fly   256 VLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICF 320
            :...:|::  :.:|:......|:...|..|..:|            ..::.:|:|..|::|.:|.
Human   186 ITAAWLIF--LFMVLCGSSLALLVRILCGSRGLP------------LTRLYLTILLTVLVFLLCG 236

  Fly   321 LPYHV-FFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHF 377
            ||:.: :||..:.|   :|....|.|: ..|:..:|..||.|||: :||..|:|||.:
Human   237 LPFGIQWFLILWIW---KDSDVLFCHI-HPVSVVLSSLNSSANPI-IYFFVGSFRKQW 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	32/110 (29%)
		7tm_1	98..364	CDD:278431	65/285 (23%)
MRGPRX2	NP_001290544.1	7tm_1	47..279	CDD:278431	66/288 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910