Protein Alignment CCHa1-R and tacr3

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_002934808.1
• Gene: tacr3 / 100486525
• XenbaseID: XB-GENE-985728
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 462
• Identity: 117/462 - (25%)
• Similarity: 199/462 - (43%)
• Gaps: 97/462 - (20%)

  Fly     5 LVSMETDLAMNIGLDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTE 69
            :.||.|:|       |:||......|:              .:...||   ..:..|.|..|..:
 Frog     1 MTSMPTNL-------TTGEVIGIFAPL--------------GEGVLWP---NSTQRNVSSPVAHK 41

  Fly    70 TPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADL-LVIIT 133
            ....|:    ...:..:.:..:..|.|.||..:|.:.|:.::||.|.|.::::||.:|. :....
 Frog    42 FVQPPW----RIALWSLAYGSMVAVAVFGNIIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFN 102

  Fly   134 TVPLASTVYTV-EYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGR 197
            |  |.:.:|.: ..|.:|...|....|....||..|:::::|::.|||.||:|||:.       |
 Frog   103 T--LVNFIYALHNEWYFGEAYCRFHNFFPITSIFASIYSMSAIAVDRYMAIIDPLKP-------R 158

  Fly   198 RATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVIC---YPYPEEWGINYAKSMVLLH 259
            .:...|.....|||:.|||...|..:.|.::    ..::..:|   :|..:| .:.|...:|||
 Frog   159 LSATSTKVVIGSIWIFAILLAFPQCLYSKIR----VTRTRTLCMLVWPGKDE-RLTYQFILVLL- 217

  Fly   260 FLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAV-RQVRARRKVAVTVLAFVVIFGICFLPY 323
               .|.:||:|:.|.|.::.:.| :...:||:..... .|:||:|||...::..||.|.||:|||
 Frog   218 ---VYVLPLIVMGVTYTIVGITL-WGGEIPGDTSDKYHEQLRAKRKVVKMMIVVVVTFAICWLPY 278

  Fly   324 HVFFL----------WFYFWPTAQDDYNA-FWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHF 377
            |:|||          |.|.    |..|.| ||         ::.:::..||:....::..||..|
 Frog   279 HIFFLADALDIKLDRWKYI----QQIYLAIFW---------LAMSSTMYNPIIYCCLNKRFRAGF 330

  Fly   378 NR-YLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTL-- 439
            .| :.:|           .......:.:..|.||   ||   |...||::.:....|:::|.:
 Frog   331 KRAFRWC-----------PFIEVSSYDELELKST---RF---HPTRQSSLYTVSRMESSMTVVFD 378

  Fly   440 PNGGNQN 446
            ||....|
 Frog   379 PNDVENN 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	87/311 (28%)
		TM helix 1	83..109	CDD:320593	6/25 (24%)
		TM helix 2	116..142	CDD:320593	6/26 (23%)
		TM helix 3	154..184	CDD:320593	10/29 (34%)
		TM helix 4	201..221	CDD:320593	7/19 (37%)
		TM helix 5	252..277	CDD:320593	9/24 (38%)
		TM helix 6	300..330	CDD:320593	17/39 (44%)
		TM helix 7	345..370	CDD:320593	2/24 (8%)
tacr3	XP_002934808.1	7tm_GPCRs	50..330	CDD:475119	87/311 (28%)
		TM helix 1	52..76	CDD:320669	5/23 (22%)
		TM helix 2	85..107	CDD:320669	6/23 (26%)
		TM helix 3	123..145	CDD:320669	5/21 (24%)
		TM helix 4	166..182	CDD:320669	6/15 (40%)
		TM helix 5	208..231	CDD:320669	9/26 (35%)
		TM helix 6	261..283	CDD:320669	10/21 (48%)
		TM helix 7	298..323	CDD:320669	7/33 (21%)