Protein Alignment CCHa1-R and kissr2

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001165296.1
• Gene: kissr2 / 100329185
• XenbaseID: XB-GENE-29077375
• Length: 369
• Species: Xenopus tropicalis
• Alignment Length: 364
• Identity: 108/364 - (29%)
• Similarity: 176/364 - (48%)
• Gaps: 50/364 - (13%)

  Fly    61 NFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLAL 125
            |.|.:..|||...|:  ..:.::||:.||||.:||::||..:|.|....||||...|.||.:||.
 Frog    21 NESLVNRTETGPPPF--LTDAWLVPLFFALIMLVGLIGNSLVIYVISKHRQMRTATNFYIANLAS 83

  Fly   126 ADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKF 190
            .|::.::..||..:|:|.:..|.:|.|:|....:::.|::..:..||||:|.||.:|.:.|||..
 Frog    84 TDIMFLVCCVPFTATLYPLPSWVFGDFMCKFVAYLQQVTVQATCITLTAMSADRCYATLYPLRSL 148

  Fly   191 HAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPY-PEEWGIN---- 250
            .     .|..::.:..::.||:.::|...|.          |..:.|...|.| |..:.|.
 Frog   149 R-----HRTPKVAMIVSICIWIGSLLLSTPI----------IPYQKIQKGYWYGPRTYCIEQFPS 198

  Fly   251 --YAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAV-----RQVRARRKVAVT 308
              ..|..:|..||..|.:||:.|.:.|.|:...:......|.:....|     |.:..|.|::..
 Frog   199 DVMKKVCILYQFLAVYLLPLLTICLCYSLMLKRVGRPVVEPTDNNYQVQLLSERTIAMRSKISKM 263

  Fly   309 VLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAF 373
            |:..|::|.||:.|..:|.|:..|:|..|.:|..:  .::..|.|||:|||..||:...|:..:|
 Frog   264 VIVIVLLFTICWGPIQLFSLFQGFYPGFQANYATY--KIKTWANCMSYANSSINPLVYAFMGASF 326

  Fly   374 RKHFNR---YLFCRGASGRRKKRGQHDTFCMHRDTSLTS 409
            ||.|.:   ::|      |.|.          ||.|:||
 Frog   327 RKSFKKAFPFMF------RNKV----------RDGSITS 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	93/306 (30%)
		TM helix 1	83..109	CDD:320593	12/25 (48%)
		TM helix 2	116..142	CDD:320593	9/25 (36%)
		TM helix 3	154..184	CDD:320593	10/29 (34%)
		TM helix 4	201..221	CDD:320593	3/19 (16%)
		TM helix 5	252..277	CDD:320593	9/24 (38%)
		TM helix 6	300..330	CDD:320593	10/29 (34%)
		TM helix 7	345..370	CDD:320593	10/24 (42%)
kissr2	NP_001165296.1	7tmA_KiSS1R	40..330	CDD:320223	93/306 (30%)
		TM helix 1	41..67	CDD:320223	12/25 (48%)
		TM helix 2	74..100	CDD:320223	9/25 (36%)
		TM helix 3	112..142	CDD:320223	10/29 (34%)
		TM helix 4	154..174	CDD:320223	3/19 (16%)
		TM helix 5	202..231	CDD:320223	10/28 (36%)
		TM helix 6	255..285	CDD:320223	10/29 (34%)
		TM helix 7	298..323	CDD:320223	10/26 (38%)