Protein Alignment CCHa1-R and tacr2

DIOPT Version :10

• Sequence 1: NP_611241.2
• Gene: CCHa1-R / 37004
• FlyBaseID: FBgn0050106
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001314788.1
• Gene: tacr2 / 100002125
• ZFINID: ZDB-GENE-090312-188
• Length: 376
• Species: Danio rerio
• Alignment Length: 341
• Identity: 90/341 - (26%)
• Similarity: 163/341 - (47%)
• Gaps: 40/341 - (11%)

  Fly    86 ILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEY---- 146
            |.:.||.::..:||.|:|.:.|:.::||.|.|.:|::||.:|     .::...:||:...|
Zfish    39 IAYTLIVIISFIGNVTVIWIILAHKRMRTVTNYFIVNLAFSD-----ASMATFNTVFNFVYALHN 98

  Fly   147 -WPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSI 210
             |.:|...|....|....::..|::::.|::.|||.||:.||:.       |.::..|......|
Zfish    99 DWYFGLGYCKFQNFFPITAMFSSIYSMAAIAVDRYMAIIHPLKP-------RLSSTTTKLLIGVI 156

  Fly   211 WLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFY 275
            |.:|.....|....::.|   ......|....:|:::|..:..|..:...::.|.:||:|:.|.|
Zfish   157 WTVAFSLAFPQCYYASTK---FYFPRTVCMVEWPDDYGGKHQLSYQIAVIILIYLLPLLVMLVTY 218

  Fly   276 VLIALHLMYSASVPGEIQGAVR-QVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDD 339
            .|:...| :.:.:|||.....: |::|:|||...::..|..|.||:||||::|:...|   .:|.
Zfish   219 SLVGQRL-WGSEIPGEASDHYQNQMQAKRKVVKMMIVVVTTFAICWLPYHIYFILGSF---NRDI 279

  Fly   340 YNAFWHVLR---IVAYCMSFANSCANPVALY------FVSGAFRKHFNRYLFCRGASGRRKKRGQ 395
            |..  |.::   :..:.::.:::..||: :|      |.|| |||.|....|.:.:.....:...
Zfish   280 YKQ--HYIQQVYLAIFWLAMSSTMYNPI-IYCCLNQRFRSG-FRKAFQWCPFVKISEEDNMELQH 340

  Fly   396 HDTFCMHRD--TSLTS 409
            ..||.|.|.  |..||
Zfish   341 MRTFHMRRSYRTETTS 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCHa1-R	NP_611241.2	7tmA_Bombesin_R-like	82..377	CDD:320593	81/305 (27%)
		TM helix 1	83..109	CDD:320593	8/22 (36%)
		TM helix 2	116..142	CDD:320593	6/25 (24%)
		TM helix 3	154..184	CDD:320593	8/29 (28%)
		TM helix 4	201..221	CDD:320593	4/19 (21%)
		TM helix 5	252..277	CDD:320593	7/24 (29%)
		TM helix 6	300..330	CDD:320593	13/29 (45%)
		TM helix 7	345..370	CDD:320593	5/33 (15%)
tacr2	NP_001314788.1	7tm_GPCRs	35..318	CDD:475119	78/301 (26%)
		TM helix 1	37..61	CDD:320670	7/21 (33%)
		TM helix 2	70..92	CDD:320670	7/26 (27%)
		TM helix 3	108..130	CDD:320670	3/21 (14%)
		TM helix 4	151..167	CDD:320670	3/15 (20%)
		TM helix 5	196..219	CDD:320670	6/22 (27%)
		TM helix 6	249..271	CDD:320670	8/21 (38%)
		TM helix 7	286..311	CDD:320670	3/25 (12%)