Protein Alignment Smurf and Yap1

DIOPT Version :9

• Sequence 1: NP_001261061.1
• Gene: Smurf / 36999
• FlyBaseID: FBgn0029006
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_006242550.1
• Gene: Yap1 / 363014
• RGDID: 1306035
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 596
• Identity: 133/596 - (22%)
• Similarity: 199/596 - (33%)
• Gaps: 198/596 - (33%)

  Fly   335 PKHQTNGHAPPE--------STPTSPTGQQ-NYVNGNAQNGSTSGNGSGQAAQPQSASNGWTQED 390
            |:....|.|||.        :.|..|.|.| .:|.|:::                      |..:
  Rat     9 PQPAPQGPAPPSVSPAGTPAAPPAPPAGHQVVHVRGDSE----------------------TDLE 51

  Fly   391 AA--TTTSPSTTTSP---PRHSQSPPTPNISPPASVTPSANGNVHSPNANSTPAGSGGGSRSYTA 450
            |.  ...:|.|...|   |...:..|.....||   .|.:    ||..| ||.||:.|      |
  Rat    52 ALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPP---EPKS----HSRQA-STDAGTAG------A 102

  Fly   451 ATPGQRSQRRSSRQQGEESSTRRRSSRGTRNGGTSGGGGGGGSGQRYASAAIAAANQAARPFLD- 514
            .||      :..|.....:|.:..:...|.:|..||            .||..||....:...:
  Rat   103 LTP------QHVRAHSSPASLQLGAGTLTASGVVSG------------PAATPAAQHLRQSSFEI 149

  Fly   515 -----LPPGYEMRTTQQGQVYFYHIPTGVSTWHDPR--------IPRDFD---TQHLTLDAIGPL 563
                 ||.|:||..|..||.||.:.....:||.|||        :|....   .|.|...|.|||
  Rat   150 PDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQDPRKAMLSQLNVPTSASPAVPQTLMNSASGPL 214

  Fly   564 PSGWEQRKTASGRVYFVDHNNRTTQFTDPRLSGSILQMIRRGTVPPTSAANAGTPAPPSATPATP 628
            |.||||..|..|.||:::|.|:||.:.||||.
  Rat   215 PDGWEQAMTQDGEVYYINHKNKTTSWLDPRLD--------------------------------- 246

  Fly   629 SAAAAVPPQATPASNATPTTLTTTTNPPHRIVPDLPQGLLEGADLLPKYRRDLVGKLRALRTELQ 693
                   |:...|.|...|.......|| .:.|..|||.:.|            |.....:.::|
  Rat   247 -------PRFGKAMNQRITQSAPVKQPP-PLAPQSPQGGVLG------------GGSSNQQQQIQ 291

  Fly   694 TMQPQSGHCRLEVSRNEIFE----ESYRLIMKMRA-----KDMRKRLMVKFKGEEG-----LDYG 744
            ..|.|....||.:.:.|:|.    ::.|.|....|     :::..|..:....::|     :...
  Rat   292 LQQLQMEKERLRLKQQELFRQVRPQAIRNINPSTANAPKCQELALRSQLPSLEQDGGTQNAVSSP 356

  Fly   745 GVAREWLHLLSREMLNP--QYGLFQYSRDD---------HYTLQINPDSGVN------------- 785
            |:.:| |..::....:|  ..|.: :|||:         .|::...||..:|
  Rat   357 GMTQE-LRTMTTNSSDPFLNSGTY-HSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQ 419

  Fly   786 ----------PDHLSYFHFVGRTLGIAVFHGHC--LDGGFTTPFYKQLLNKPITLGDIEGV---- 834
                      ||:|.  ...|..:.:....|..  ::|....|..::.|:..|.  |:|.|
  Rat   420 STLPSQQSRFPDYLE--ALPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSEIL--DVESVLAAT 480

  Fly   835 DPDLHRSLTWM 845
            ..|....|||:
  Rat   481 KLDKESFLTWL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smurf	NP_001261061.1	C2_Smurf-like	14..135	CDD:176028
		WW	169..198	CDD:278809
		WW	514..546	CDD:197736	15/45 (33%)
		WW	562..594	CDD:197736	17/31 (55%)
		HECTc	702..1058	CDD:238033	37/198 (19%)
		HECTc	726..1058	CDD:214523	30/165 (18%)
Yap1	XP_006242550.1	WW	156..185	CDD:238122	12/28 (43%)
		WW	213..245	CDD:197736	17/31 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910