Protein Alignment Smurf and yap-1

DIOPT Version :9

• Sequence 1: NP_001261061.1
• Gene: Smurf / 36999
• FlyBaseID: FBgn0029006
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001369894.1
• Gene: yap-1 / 181267
• WormBaseID: WBGene00008748
• Length: 442
• Species: Caenorhabditis elegans
• Alignment Length: 292
• Identity: 64/292 - (21%)
• Similarity: 94/292 - (32%)
• Gaps: 119/292 - (40%)

  Fly   324 RLHSNDNHVKTP-----KHQ-----TNGHAP----PESTPTSPTGQQNYVNGNAQNGSTSGNGSG 374
            :...|.|..|.|     .||     ::.|:|    .||:.|:.:...:.|:..|...:.
 Worm    43 KYEKNQNQKKNPLPSSYYHQKRNPGSSAHSPYGSVDESSRTAVSPAMDMVSNQAPIHTR------ 101

  Fly   375 QAAQPQ---SASNGWTQEDAATTTSPSTTTSPPRHSQS----PPTPNISPPASVTPSANGNVHSP 432
            |.:.|.   |.:||   :.:||...||......:||:|    |.|...||..|...|.:   |..
 Worm   102 QVSAPNLHTSVNNG---QSSATVPHPSHHNVHHQHSKSVSALPMTIGYSPVPSHVKSVS---HEA 160

  Fly   433 NANSTPAGSGGGSRSYTAATPGQRSQRRSSRQQGEESSTRRRSSRGTRNGGTSGGGGGGGSGQRY 497
            |              |:.|...:..|::...||..|.|
 Worm   161 N--------------YSYAGLSEIPQQQGMMQQNREKS--------------------------- 184

  Fly   498 ASAAIAAANQAARPFLDLPPGYEMRTTQQGQVYFYHIPTGVSTWHDPRIPRDFDTQHLTLDAIGP 562
                 .:.:...|||:          |.|                        |.:.|      |
 Worm   185 -----LSLDPMRRPFM----------TPQ------------------------DVEQL------P 204

  Fly   563 LPSGWEQRKTASGRVYFVDHNNRTTQFTDPRL 594
            :|.|||....:.|..||.|||::||.:.||||
 Worm   205 MPQGWEMCYDSDGVRYFKDHNSKTTTWDDPRL 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smurf	NP_001261061.1	C2_Smurf-like	14..135	CDD:176028
		WW	169..198	CDD:278809
		WW	514..546	CDD:197736	2/31 (6%)
		WW	562..594	CDD:197736	15/31 (48%)
		HECTc	702..1058	CDD:238033
		HECTc	726..1058	CDD:214523
yap-1	NP_001369894.1	WW	206..236	CDD:238122	14/29 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900