DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-51L1 and Ndufv1

DIOPT Version :9

Sequence 1:	NP_611238.2	Gene:	ND-51L1 / 36998	FlyBaseID:	FBgn0034251	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_598427.1	Gene:	Ndufv1 / 17995	MGIID:	107851	Length:	464	Species:	Mus musculus

Alignment Length:	438	Identity:	326/438 - (74%)
Similarity:	378/438 - (86%)	Gaps:	1/438 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 GTPPPQTKTTFGPLADADRIFTNLYGRHDWRLKAAMKRGDWYKTKEIIAKGDKWIVNEIKTSGLR 309
            ||..|: ||:||.|.|.||||||||||||||||.|::||||||||||:.||..||:.|:||||||
Mouse    23 GTTAPK-KTSFGSLKDEDRIFTNLYGRHDWRLKGALRRGDWYKTKEILLKGPDWILGEMKTSGLR 86

  Fly   310 GRGGAGFPSGLKWSFMHKPPDGRPKFLVVNADEGEPGTCKDREIMRHDPHKLVEGCLIAGRAMGA 374
            ||||||||:|||||||:||.|||||:|||||||||||||||||||||||||||||||:.||||||
Mouse    87 GRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLVGGRAMGA 151

  Fly   375 NTGFIYIRGEFYNEACNLQYAIIEAYKAGYLGKNACGSGFDFDLYVQRGAGAYICGEETSLIESL 439
            ...:|||||||||||.|||.||.|||:||.:|||||||.:|||::|.||||||||||||:||||:
Mouse   152 RAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSDYDFDVFVVRGAGAYICGEETALIESI 216

  Fly   440 EGKAGKPRNKPPFPADIGVFGCPSTVTNVETVAVSPTICRRGGNWFASFGRTRNSGTKLFNISGH 504
            |||.||||.|||||||:||||||:||.||||||||||||||||.|||.|||.|||||||||||||
Mouse   217 EGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLFNISGH 281

  Fly   505 VCNPCTVEEEMSMPTRELIERHAGGVIGGWDNLLAIIPGGSSTPCITKEHASSAIHDYDGLMAVR 569
            |.:|||||||||:|.:||||:|||||.||||||||:||||||||.|.|....:.:.|:|.|:..:
Mouse   282 VNHPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQ 346

  Fly   570 SSMGTGALIVMNKDTDIIKAIARLSAFYKHESCGQCTPCREGLHWVNMIMHRFVTGQAQIAEIDM 634
            :.:||.|:|||::.|||:||||||..||||||||||||||||:.|:|.:|.|||.|.|:.||||.
Mouse   347 TGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVKGDARPAEIDS 411

  Fly   635 LFELTKQIEGHTICALADGAAWPPQGLIRNFRPVIEERIKKRAAEDQA 682
            |:|::|||||||||||.||||||.|||||:|||.:|:|:::.|.:.:|
Mouse   412 LWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEDRMQRFAQQHRA 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-51L1	NP_611238.2	CAP_N	<195..234	CDD:279545
		PRK13596	258..688	CDD:237441	319/425 (75%)
		Complex1_51K	303..472	CDD:279808	139/168 (83%)
		NADH_4Fe-4S	589..670	CDD:287548	60/80 (75%)
Ndufv1	NP_598427.1	PRK13596	35..463	CDD:237441	319/425 (75%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1894
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1523
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003103
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101044
Panther	1	1.100	-	-	O	PTHR11780
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.650