DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment icln and clns1a

DIOPT Version :9

Sequence 1:	NP_611237.2	Gene:	icln / 36997	FlyBaseID:	FBgn0029079	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_571499.2	Gene:	clns1a / 30699	ZFINID:	ZDB-GENE-990415-259	Length:	249	Species:	Danio rerio

Alignment Length:	232	Identity:	71/232 - (30%)
Similarity:	107/232 - (46%)	Gaps:	51/232 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLIMRVSPPEHGLLYTANNIKLKLGDKVVGEGTVYIAQNTLSWQPTELAEGISIEWKQVSLHGI 65
            |||:..:.||..|:..........|..|.:|.||:::|:..|||.... ..|..:|:..:|||.|
Zfish     1 MVLLKSLPPPSEGVRLQQAETTAVLDGKRLGLGTLFVAEAQLSWFDGS-GMGFCLEYPTISLHAI 64

  Fly    66 SSN----PRKCIYFMLDHKVEWNGVYGDPPQQAVNGRNGGGSEAEVDEGNGS----DEHDEDDNF 122
            |.:    |.:.:|.|::.|::                         |||..:    |..:||:|.
Zfish    65 SRDLSAFPEEHLYVMVNAKLD-------------------------DEGEAAPLEKDPDEEDENE 104

  Fly   123 EDAVDEQFGEVTECWLMPEDIHTVDTMYSAMTTCQALHPDSANSDSEDSDPMQDAGGLE---DEA 184
            ||:..|..||:||...:|.|...::.|:|||..|||||||..::||||.|   |..|.|   :||
Zfish   105 EDSDSEGSGEITEIRFVPSDKAALEPMFSAMCDCQALHPDPDDADSEDDD---DYEGEEYDVEEA 166

  Fly   185 MEEDDALTLG--------RNGVQNLSLDDDE--ERFE 211
             |::.|...|        ..|:.:|:.:...  ||.|
Zfish   167 -EQEQAQAHGDIPSFYTYEEGLSHLTAEGQATLERLE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
icln	NP_611237.2	Voldacs	33..189	CDD:281511	55/166 (33%)
clns1a	NP_571499.2	Voldacs	33..>143	CDD:281511	41/135 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581501
Domainoid	1	1.000	77	1.000	Domainoid score	I8835
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I5110
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1508796at2759
OrthoFinder	1	1.000	-	-		FOG0006470
OrthoInspector	1	1.000	-	-		oto38677
orthoMCL	1	0.900	-	-		OOG6_103509
Panther	1	1.100	-	-	LDO	PTHR21399
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.900