Protein Alignment RhoGAP54D and SAC7

DIOPT Version :10

• Sequence 1: NP_611236.2
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_010677.1
• Gene: SAC7 / 851997
• SGDID: S000002797
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 523
• Identity: 103/523 - (19%)
• Similarity: 185/523 - (35%)
• Gaps: 149/523 - (28%)

  Fly   129 LTQEGLFRKAGAVSRQNELRMHIQHDKP-----LNLELAGFSAHDCATVFKGFLSELPEPLLTDA 188
            |...|:||.||...|...|: :|....|     .| :...::.||.|::.:.:|:.|.|||:..:
Yeast   166 LETSGIFRIAGNGKRVKALQ-YIFSSPPDYGTKFN-DWETYTVHDVASLLRRYLNNLAEPLIPLS 228

  Fly   189 -----------------HYPAHLQIAPLCQALNGQTTATAERQQH-------------------- 216
                             |...|....|.....| ..|..:.||.:
Yeast   229 LYEQFRNPLRSRPRILRHMLTHEVSHPNANKTN-NVTVKSSRQNYNDDGANDGDIEKEDAKDDEE 292

  Fly   217 ------------------LLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKHEKSNKMSADNLATL 263
                              .:...:.|.:.|..:.::|..:::::|...|:..:.|.||..|||.:
Yeast   293 KRRRKIRHKRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAI 357

  Fly   264 FTPHLICPRQLPPEVLHYQAKKMSSIVTYMIVRGLDIFEVPGKLSTDIRAYFLERKRKKTMSPEQ 328
            |.|.::...|...:...|:..::  :|.::|.....:.....||:...:...|..:.||....:|
Yeast   358 FQPSILSHPQHDMDPKEYELSRL--VVEFLIEYSYKLLPHLLKLAKREQQERLSTENKKNNGDKQ 420

  Fly   329 TLDE-SISDVSTVNTVYTFVDRAATAAATNTNNTD-TELAQLYAHIQSMPESS------------ 379
            ..|. .|..:::.::...........|..|.|..| |.|:.:..   |:||:|
Yeast   421 KTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPIST---SIPENSSDLQTSKMLKPP 482

  Fly   380 KKRRLIKQFNKQNGQGTPL--QLVVMNRLK------------------NNEATRSAKSLGDSIKK 424
            |:||   ..:|..| .||:  .::..|:.:                  |.:.| :.::.||..::
Yeast   483 KQRR---PHSKSFG-STPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLT-ATEAEGDDYEE 542

  Fly   425 HIFHKSLMSRTPKRVPPSFHLASGSETPNMSHVKPPKM-RVLFQSPTPPT----PTSSTITS--- 481
            ........|      |.|.|  ||| .|...::..|:| |.|..:.|..:    |.|..:||
Yeast   543 ENVDPYGQS------PSSVH--SGS-LPKQHYLPIPRMNRSLSGNSTNSSFNTRPISMILTSGND 598

  Fly   482 -----VSLSTNTRHQLQKSISSASLKIESSSSDSSSSCATSGSISAPVSRQQSKES-----PSGN 536
                 :.|.:||....::   |.:|.:.....|..:            ||.:.:||     .|.:
Yeast   599 NSADQLELLSNTHSNNER---SNALPLTEDDGDERN------------SRSRKRESWFQRLTSRS 648

  Fly   537 GAA 539
            |:|
Yeast   649 GSA 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_611236.2	RhoGAP	107..313	CDD:470621	45/243 (19%)
SAC7	NP_010677.1	RhoGAP_fSAC7_BAG7	122..393	CDD:239861	43/231 (19%)