Protein Alignment RhoGAP54D and arhgap18

DIOPT Version :9

• Sequence 1: NP_001261060.1
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001072336.1
• Gene: arhgap18 / 779789
• XenbaseID: XB-GENE-988160
• Length: 662
• Species: Xenopus tropicalis
• Alignment Length: 418
• Identity: 98/418 - (23%)
• Similarity: 169/418 - (40%)
• Gaps: 99/418 - (23%)

  Fly     1 MEATMDTDHANLNDFRDRDLATRMRRCNYEKYKSLV-RMHLSFELELNTDEFDLPCHEI------ 58
            :|.:.....:||.||      ||:|  |.::..||: ...|:.:....|...||...::
 Frog   229 LEISFAEQASNLKDF------TRVR--NEKEDDSLLPNFRLTQDKTGTTKIGDLAPQDMKKVSSL 285

  Fly    59 -------VYEDKGKLKKWNRLSK-KHRLGHGAAATSCAAGSASKSVGNSPTETL---QQQIDPGF 112
                   :|:..|...|..|.:| |.|               ...:...|..||   .|:..||.
 Frog   286 ALIELTALYDVLGTELKMQRAAKIKVR---------------ESGLFRVPLSTLLDQDQKRAPGT 335

  Fly   113 LMHLQELKEFLMLEK-NLTQEGLFRKAGAVSRQNELRMHIQ---HDKPLNLELAGFSAHDCATVF 173
            .:.|........:|| .|..||:.|..||.:|...|...::   ::...|.:  ....||.|::.
 Frog   336 RVPLIFQSLIGHIEKGGLDTEGILRIPGASARIKALIEELEAKFYEGTFNWD--NVKQHDAASLL 398

  Fly   174 KGFLSELPEPLLTDAHYPA--HLQIAPLCQALNGQTTATAERQQHLLNSVQLLLLLLPEEHRELL 236
            |.|:.|||.||||..:..|  .:|..|              .::|.|.::.||::||||.||:.|
 Frog   399 KFFIRELPLPLLTVEYLKAFHSVQYLP--------------TKKHRLQALNLLVILLPEIHRDTL 449

  Fly   237 QHIIEMLHAVAKHEKSNKMSADNLATLFTPHLICPRQLPPEVLHYQAK--------------KMS 287
            :.::|.|..|..|.:.|||...|:|.:..|:|.       .|..||.|              :.:
 Frog   450 KALLEFLQRVVDHREQNKMILKNVAMIMAPNLF-------SVHTYQLKTVDQGALEGAFSAARTA 507

  Fly   288 SIVTYMIVRGLDIFEVPGKLSTDIRAYFLERKRKKTMSPEQTLDESISDVSTVNTVYTFVDRAAT 352
            |::.:||.....::.:|..:...:|...:..::|  :|.|:.:.:.:..::        .||..:
 Frog   508 SVMLFMIKYQNLLWTIPKFIVAQVRRQNIVNQKK--LSKEKPMKKLLKRMA--------YDREKS 562

  Fly   353 AAATNTNNTDTELAQLYAHIQSMPESSK 380
            ...|:.|    :..|.:..:|: |:.||
 Frog   563 EKCTSEN----DAPQGFIRVQA-PQFSK 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	59/225 (26%)
arhgap18	NP_001072336.1	RhoGAP_ARHGAP18	316..532	CDD:239856	63/238 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910