Protein Alignment RhoGAP54D and Arhgap45

DIOPT Version :9

• Sequence 1: NP_001261060.1
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001334003.1
• Gene: Arhgap45 / 70719
• MGIID: 1917969
• Length: 1127
• Species: Mus musculus
• Alignment Length: 379
• Identity: 85/379 - (22%)
• Similarity: 144/379 - (37%)
• Gaps: 97/379 - (25%)

  Fly   129 LTQEGLFRKAGAVSRQNELRMHIQHDKPLNLELAGFSAHDCATVFKGFLSELPEPLLTDAHYPAH 193
            |..:|::|..|..:|..:|....::.|.| :||:..|.||.:.|.|.:|.:|||||::...|  |
Mouse   798 LHTKGIYRVNGVKTRVEKLCQAFENGKEL-VELSQASPHDISNVLKLYLRQLPEPLISFRFY--H 859

  Fly   194 LQIAPLCQALNGQTTATAERQQH------------LLNSVQLLLLLLPEEHRELLQHIIEMLHAV 246
            ..:.....:|..:..|.|..:..            ::..::.|:..||.|:|..|.::::.|..:
Mouse   860 ELVGLAKDSLKAEAEAKAASRGRQGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRI 924

  Fly   247 AKHEKSNKMSADNLATLFTPHLICPRQLPPEVLHYQAKKMSSIVTY---------MIVR-GLDIF 301
            .:.|:.|||:..||..:|.|.|:.||.....|      .:||:|.|         :||. || :|
Mouse   925 VEMEQDNKMTPGNLGIVFGPTLLRPRPTDATV------SLSSLVDYPHQARVIETLIVHYGL-VF 982

  Fly   302 EVPGKLSTDIRAYFLERKRKKTMSPEQTLDESISDVSTVNTVYTFVDRA-----ATAAATNTNNT 361
            |              |...:...|.|....:.....|....|:...:.|     .:.||:|.:::
Mouse   983 E--------------EEPEEAPGSQEGASTQCGQLESAEGIVFPLQEEAEDGSRESHAASNDSDS 1033

  Fly   362 DTE-------------------LAQLYAHIQSMPESSKKRRLIKQFNKQNGQGTPLQLVVMNRLK 407
            :.|                   |.|..|.::..|:|.....  :|...::|...| .|...|..:
Mouse  1034 ELEDASDPLSSSDASALHRLSFLEQTEAGLEEGPQSHSGSE--EQLEGEDGAPGP-WLCHFNTNQ 1095

  Fly   408 NNEATRSAKSLGDSIKKHIFHKSLMSRTPKRVPPSFHLASGSETPNMSHVKPPK 461
            :|..                     ||.|.   |:..|..|..|...|..:.|:
Mouse  1096 SNNT---------------------SRAPL---PTMRLRGGQITGGTSQERQPQ 1125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	55/205 (27%)
Arhgap45	NP_001334003.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1453
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900