| Sequence 1: | NP_001261060.1 | Gene: | RhoGAP54D / 36996 | FlyBaseID: | FBgn0034249 | Length: | 1004 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004136.2 | Gene: | MYO9B / 4650 | HGNCID: | 7609 | Length: | 2157 | Species: | Homo sapiens |
| Alignment Length: | 474 | Identity: | 118/474 - (24%) |
|---|---|---|---|
| Similarity: | 188/474 - (39%) | Gaps: | 95/474 - (20%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 79 GH-GAAATSCAAGSASKSVGNSPTETLQQQIDPGFLMHLQELKEFLMLEKNLTQEGLFRKAGAVS 142
Fly 143 RQNELRMHIQHDKPLNLELAGFSAHDCATVFKGFLSELPEPLLTDAHYPAHLQIAPLCQALNGQT 207
Fly 208 TATAERQQHLLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKHEKSNKMSADNLATLFTPHLI-CP 271
Fly 272 RQLPPEVLHYQAKKMSSIVTYMI--------VRGLDIFEVPGKLSTDIRAYFLERK------RKK 322
Fly 323 TMSP-EQTLDES--ISDVSTVNTVYTFVDRAATAAATNTNNTDTELAQLYAHIQSMPESSKKRRL 384
Fly 385 IKQFNKQNGQGTPLQLVVMNRLKNNEATRSAKSLGDSIKKHIFHKSLMSRTPKRVPPSFHL-ASG 448
Fly 449 SETPNMSHVKPPKMRVLFQSPT---PPTPTSSTITSVSLSTNTRHQLQKSISSASLKIESSSSDS 510
Fly 511 SSSCATSG-SISAPVSRQQ 528 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| RhoGAP54D | NP_001261060.1 | RhoGAP | 107..313 | CDD:295372 | 64/214 (30%) |
| MYO9B | NP_004136.2 | Myosin_IXb_RA | 7..112 | CDD:176374 | |
| MYSc | 141..950 | CDD:214580 | |||
| MYSc_Myo9 | 160..941 | CDD:276836 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 709..734 | ||||
| Actin-binding. /evidence=ECO:0000305 | 844..855 | ||||
| Neck or regulatory domain. /evidence=ECO:0000305 | 940..1044 | ||||
| IQ | 978..999 | CDD:197470 | |||
| IQ | 1000..1022 | CDD:197470 | |||
| Tail. /evidence=ECO:0000305 | 1045..2157 | 118/474 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1046..1298 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1320..1410 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1455..1484 | ||||
| C1 | 1633..1681 | CDD:237996 | |||
| RhoGAP_myosin_IXB | 1698..1883 | CDD:239872 | 67/216 (31%) | ||
| Interaction with RHOA. /evidence=ECO:0000269|PubMed:26529257 | 1739..1744 | 2/4 (50%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1980..2157 | 27/150 (18%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1453 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||