Protein Alignment RhoGAP54D and Arhgap18

DIOPT Version :9

• Sequence 1: NP_001261060.1
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001164046.1
• Gene: Arhgap18 / 293947
• RGDID: 1305053
• Length: 665
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 105/459 - (22%)
• Similarity: 184/459 - (40%)
• Gaps: 91/459 - (19%)

  Fly     1 MEATMDTDHANLNDFR---DRDLATRMRRCNYEKYKSLVRMHLSFELELNTDEFDLPCHEIVYED 62
            |:.|...| |:|..||   |:...||:.....:..|.:..:.|   :||..          :|:.
  Rat   253 MQKTRGND-ASLPSFRLPKDKTGTTRIGDLAPQDMKKVCYLSL---IELTA----------LYDV 303

  Fly    63 KG-KLKKWNRLSKKHRLGHGAAATSCAAGSASKSVGNSPTETLQQQID---PGFLMHLQELKEFL 123
            .| :||:...:..|.|               ...:...|...|.:|..   ||..:.|...|...
  Rat   304 LGVELKQQKAVKIKTR---------------DSGLFGIPLTILLEQDQRKVPGTRIPLIFQKLIS 353

  Fly   124 MLEK-NLTQEGLFRKAGAVSRQNELRMHIQ---HDKPLNLELAGFSAHDCATVFKGFLSELPEPL 184
            .:|: :|..|||.|..||..|...|...::   ::...|.|  ....||.|::.|.||.|||:||
  Rat   354 CIEEGSLETEGLLRIPGAAMRVKNLCQELEAKFYEGTFNWE--SVKQHDAASLLKLFLRELPQPL 416

  Fly   185 LTDAHYPAHLQIAPLCQALNGQTTATAERQQHLLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKH 249
            |:..:..|.       ||:  |...|.:.|...||   ||::|||:.:|:.|:.::|.|..|..:
  Rat   417 LSTEYLKAF-------QAV--QNLPTKKEQLQALN---LLVILLPDANRDTLKALLEFLQRVIDN 469

  Fly   250 EKSNKMSADNLATLFTPHLICPRQLPPEVLHYQ--------AKKMSSIVTYMIVRGLDIFEVPGK 306
            ::.|||:|.|:|.:..|:|.....|..:...::        |..|..::.|..:    ::.:|..
  Rat   470 KEKNKMTAVNVAMVMAPNLFMCHALGLKSSEHREFEMAAGTANTMHLLIRYQKL----LWTIPKF 530

  Fly   307 LSTDIRAYFLERKRKKTMSPEQTLDESISDVSTVNTVYTFVDRAATAAATNTNNTDT-------- 363
            :...:|.:....::|:..:.::.|.:...|    ...:...||||       |..|.
  Rat   531 IVNQVRKHNTAHQKKERRAMKKLLKKMAYD----REKHEKQDRAA-------NGADVPQGVIRVQ 584

  Fly   364 --ELAQLYAHIQSMPESSKKRRLIKQFNKQNGQGTPLQL--VVMNRLKNNEATRSAKSLGDSIKK 424
              .|:::...||...|......|.:..::::|....|:.  |.:..:..|...|....  |:..|
  Rat   585 APHLSKVSMAIQLTEELKASDVLARFLSQESGVAQTLKKGEVFLYEIGGNIGERCLDD--DTYMK 647

  Fly   425 HIFH 428
            .::|
  Rat   648 DLYH 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	60/220 (27%)
Arhgap18	NP_001164046.1	RhoGAP_ARHGAP18	323..536	CDD:239856	62/230 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910