DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP54D and chin-1

DIOPT Version :9

Sequence 1:	NP_001261060.1	Gene:	RhoGAP54D / 36996	FlyBaseID:	FBgn0034249	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_497323.3	Gene:	chin-1 / 175268	WormBaseID:	WBGene00015267	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	160	Identity:	43/160 - (26%)
Similarity:	77/160 - (48%)	Gaps:	16/160 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 KNLTQEGLFRKAGAVSRQNELRMHIQHDKPLNLELAGF-SAHDCATVFKGFLSELPEPLLTDAHY 190
            :.|..||::|.:|:.....:|:.  |.|....::||.. ..|....:.|.:...||:.|:.   :
Worm   261 RGLDVEGIYRVSGSYDHMEKLKQ--QFDSNQYVDLATVCDIHTVCGLLKLYFRLLPQQLIP---F 320

  Fly   191 PAHLQIAPLCQALNGQTTATAERQQHLLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKHEKSNKM 255
            ..|.|:....|..|.::|...|||      ::.:::.|.:.:...|..::..|..||.|...|||
Worm   321 SVHKQLLVAYQETNQRSTHERERQ------IRKVMMELSDANIITLGAVLAHLKKVADHSAKNKM 379

  Fly   256 SADNLATLFTPHLICPRQLPP----EVLHY 281
            :.:||||:|:|.|.|...:|.    ::||:
Worm   380 TVENLATIFSPTLFCSGSIPAMPNHQLLHF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	43/160 (27%)
chin-1	NP_497323.3	SH2_a2chimerin_b2chimerin	43..130	CDD:198215
		C1_1	172..224	CDD:278556
		RhoGAP	248..413	CDD:238090	43/160 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1453
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900