Protein Alignment RhoGAP54D and LOC1278822

DIOPT Version :10

• Sequence 1: NP_611236.2
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_061507801.1
• Gene: LOC1278822 / 1278822
• VectorBaseID: AGAMI1_005641
• Length: 3010
• Species: Anopheles gambiae
• Alignment Length: 875
• Identity: 178/875 - (20%)
• Similarity: 303/875 - (34%)
• Gaps: 247/875 - (28%)

  Fly     8 DHANLNDFRDR----DLATRMRRCNYEKYKSLVRMHLSFELE--LNTDEFDLPCHEIVYEDKGKL 66
            ||...|....:    ::||....|         :..|.:.:|  |......|.||:..|:.....
Mosquito  2199 DHTTFNGHTFQLTILNIATACEIC---------QQFLLWPIERGLVCQNCKLTCHKKCYQKSASC 2254

  Fly    67 KKWNRLSKKHRLGHGAAATSCAAGSASKS-----VGNSPTE-------TLQQQIDPGFLMHLQEL 119
            .|.........||.|.:.::..||.....     .|..||:       .|......|..:..|..
Mosquito  2255 NKIANADPNSLLGAGGSGSAVVAGGCGPDGQPLYGGGIPTKLFGVPLTALCGNSSDGVKIPAQIN 2319

  Fly   120 KEFLMLEKN-LTQEGLFRKAGAVSRQNELRMHIQHDKPL--------NLELAGFSAHDCATVFKG 175
            |..:|:|.: |..||::||:|..|:..:|:..:  |:.:        .::...::.|....|.|.
Mosquito  2320 KLIMMIEMHGLYSEGIYRKSGVSSKIKDLKAKM--DRAVTSADGGGGEMDFESYNVHVLTNVLKS 2382

  Fly   176 FLSELPEPLLTDAHYPAHLQIAPLCQALNGQTTATAERQQHLLNSVQLLLLLLPEEHRELLQHII 240
            ||.|:||||||...|...|:.|.|...        ::|.|.||:    |:..:|..|..|.:.:|
Mosquito  2383 FLREMPEPLLTFDRYDDFLRAADLSDG--------SDRVQTLLS----LVKKIPPAHHCLFERLI 2435

  Fly   241 EMLHAVAKHEKSNKMSADNLATLFTPHLI-----CPRQLPPEVLHYQAKKMSSIVTYMIVRGLDI 300
            ..|..|||.|:.|:|||.:||.:|.|.::     .|.|.....:..|.|.|.:::|..:   |::
Mosquito  2436 FHLALVAKLEQYNRMSASSLAIVFAPCVLRTNRYVPAQDSLNDIGRQTKCMETLITQKM---LNV 2497

  Fly   301 FEVPGKLSTDIRAYFLERKRKKTMSPEQTLD----ESISDVSTVNTVYTFVDRAATAAATNTN-- 359
                                |.|::...|||    .:.:.:||:.:...|.......|...:.
Mosquito  2498 --------------------KSTLADIDTLDTAAHTATARLSTLRSSKVFTQEEMANARGGSGIA 2542

  Fly   360 -----NTDTELAQLYAHIQSMPESSKKRRLIKQ---------------FNKQNGQGTPLQLVVMN 404
                 .|:||...|..|||   |..|::.|:..               ....:|:|..|..:..:
Mosquito  2543 VGGLLETETEEMLLEGHIQ---EIRKEKALLTSTLPSLARASSDDDLLSTDLDGEGGSLDDLSNS 2604

  Fly   405 RLKNNEATR--------------SAKSLGD---SIKKHI-------FHKSLMSRTPKRVPPS--- 442
            :.|:.:.:.              |:..:.|   ||:...       .:.||.:..|..|..|
Mosquito  2605 KEKDLDVSSGGGGGGGGGGGGGGSSNMISDSGISIRYQAPSDHGGSSNVSLNNDVPMAVSYSLRD 2669

  Fly   443 ----------------------FH---------LASGSETPNMSHVKPPKMRVLFQS------PT 470
                                  ||         .|.|.:|.::||....:.....:.      .:
Mosquito  2670 QSGAGGAGGGGGGGASAAGMEYFHKMGPSSGASSAPGVKTKSLSHQTLLEREAFLRGSGSTSVSS 2734

  Fly   471 PPTPTSSTITSVSLSTNTRHQLQKSISSASLKIESSSSDSSSSCATSGSISAPVSRQQSKESPSG 535
            |.:||::|..:.|.:.::      |.|:.|:......:.:.::.:|.|:.:...|...|.....|
Mosquito  2735 PQSPTAATSVTASSTPSS------SASAPSMMKSQQQNGNGANGSTGGASAGGASAAGSGTGGGG 2793

  Fly   536 NGA----------AGASGQELDEIDADCCVTPLKIMS-----------------------AVAKQ 567
            .|:          :||:|:...:|:....:..|...|                       .....
Mosquito  2794 PGSGGSIASTATNSGAAGKRASDINLSHSMITLATTSHSLGGSTTSNSSSSGVGGSSGSTGSGSD 2858

  Fly   568 LIDKKSVAWDEHRLLEIEEYSNP-----STPVQQSTRYKSEPNLSSILP-----QVDAEEEDDGA 622
            |..:|.::.......|:..:.:.     |.....||.::.....||.||     .:.|.....|:
Mosquito  2859 LQRQKPISRSVSGGYEVSHHGSTVSGSGSGSTHASTNHRILIQASSALPITPGATIAASPSGSGS 2923

  Fly   623 LTPIVEGRSTMVASSSHMGRSITRKLMKGV-------SMGNLRFPFSTPETTKRLVRSVSATLRR 680
                 ...||..:|||....::..|...|:       |.||    .||..|||.:.|.:||...:
Mosquito  2924 -----GATSTSASSSSINSANLHAKDNNGMGKDGLSSSGGN----SSTTTTTKLVSRRMSAGTNK 2979

  Fly   681 R------PSGEESKPC-----PLAADAPLL 699
            |      |||..:...     |...|.|::
Mosquito  2980 RSGGGAGPSGGSNSAAGGPGPPAGDDEPIM 3009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_611236.2	RhoGAP	107..313	CDD:470621	59/219 (27%)
LOC1278822	XP_061507801.1	None