Protein Alignment RhoGAP54D and CHN2

DIOPT Version :9

• Sequence 1: NP_001261060.1
• Gene: RhoGAP54D / 36996
• FlyBaseID: FBgn0034249
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_016867210.1
• Gene: CHN2 / 1124
• HGNCID: 1944
• Length: 575
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 74/312 - (23%)
• Similarity: 119/312 - (38%)
• Gaps: 77/312 - (24%)

  Fly    30 EKYKSLVRM--------HLSFELELNTDEFDLPCHEIVYEDKGKLKKWNRLSKKHRLG---HGAA 83
            ||..||||.        |.::|   .|..|.      |:..:|  ..|.........|   .|..
Human   298 EKISSLVRRAALTHNDNHFNYE---KTHNFK------VHTFRG--PHWCEYCANFMWGLIAQGVR 351

  Fly    84 ATSCAAG---SASKSVGNSPTETLQQ-----QIDPGFLMHLQELKEFLMLE--------KNLTQE 132
            .:.|...   ..||.|.|.....|::     ..|...|:.....:..::::        :.|..|
Human   352 CSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSE 416

  Fly   133 GLFRKAGAVSRQNELRMHIQHDKPLNLELAGFSAHDCATV------FKGFLSELPEPLLTDAHYP 191
            ||:|.:|......:::|....|.    |.|..||:....:      .|.:..:||.|::|...|.
Human   417 GLYRVSGFTEHIEDVKMAFDRDG----EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYS 477

  Fly   192 AHLQIAPLCQALNGQTTATAERQQHLLNSVQLLLLLLPEEHRELLQHIIEMLHAVAKHEKSNKMS 256
            ..:..|.:..|        .||    |.:|..:|:|||..|.|.|::::..|..|..:||.|.|:
Human   478 KFIDAAKISNA--------DER----LEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMN 530

  Fly   257 ADNLATLFTPHLICPRQLPPE-----VLH---YQAKKMSSIVTYMIVRGLDI 300
            |:||..:|.|.|:    .|||     .||   ||     .::..:::...|:
Human   531 AENLGIVFGPTLM----RPPEDSTLTTLHDMRYQ-----KLIVQILIENEDV 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP54D	NP_001261060.1	RhoGAP	107..313	CDD:295372	53/216 (25%)
CHN2	XP_016867210.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1453
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900